1. 重组蛋白
  2. Enzymes & Regulators
  3. Hydrolases (EC 3)
  4. Coagulation Factor XIV/PROC 蛋白, Mouse (HEK293, His)

Coagulation Factor XIV/PROC 蛋白, Mouse (HEK293, His)

目录号: HY-P74236
COA 产品使用指南

XIV/PROC 因子蛋白(或蛋白 C)是一种重要的维生素 K 依赖性丝氨酸蛋白酶,可调节血液凝固。蛋白 C 在灭活因子 Va 和 VIIIa 以及在钙离子和磷脂存在的情况下调节凝血级联中起着至关重要的作用。Coagulation Factor XIV/PROC 蛋白, Mouse (HEK293, His) 是重组的 凝血因子 XIV/PROC 蛋白,由 HEK293 表达,带有 C-His 标签。Coagulation Factor XIV/PROC 蛋白, Mouse (HEK293, His) 全长 442 个氨基酸,分子量分别约为 ~63 & 45 kDa。

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规格 价格 是否有货 数量
10 μg ¥1650 In-stock
20 μg ¥2800 In-stock
50 μg   询价  
100 μg   询价  

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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

Factor XIV/PROC protein (or protein C) is an important vitamin K-dependent serine protease that regulates blood clotting. Protein C plays a crucial role in inactivating factors Va and VIIIa and regulating the coagulation cascade in the presence of calcium ions and phospholipids. Coagulation Factor XIV/PROC Protein, Mouse (HEK293, His) is the recombinant mouse-derived Coagulation Factor XIV/PROC protein, expressed by HEK293 , with C-His labeled tag. The total length of Coagulation Factor XIV/PROC Protein, Mouse (HEK293, His) is 442 a.a., with molecular weight of ~63 & 45 kDa, respectively.

研究背景

凝血因子 XIV/PROC 蛋白,也称为蛋白 C,是一种关键的维生素 K 依赖性丝氨酸蛋白酶,对于调节凝血至关重要。蛋白 C 在钙离子和磷脂存在下发挥作用,在因子 Va 和 VIIIa 失活中发挥关键作用,从而调节凝血级联。除了止血作用之外,蛋白 C 还将其影响扩展到内皮细胞屏障功能,发挥保护作用。这种双重功能强调了凝血因子 XIV/PROC 蛋白在维持血液凝固和内皮完整性的微妙平衡方面的重要性,强调了其在生理过程中的复杂参与。

生物活性

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

种属

Mouse

表达系统

HEK293

标签

C-His

蛋白编号

P33587 (I19-L460)

基因 ID

19123  [NCBI]

蛋白结构
N-term
PROC (I19-L460)
Accession # P33587
His
C-term
同用名
Vitamin K-dependent protein C; APC; Protein C; PROC
分子量

Approximately 63&45 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

性状

无菌粉末.

组分

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

Coagulation Factor XIV/PROC Protein, Mouse (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Coagulation Factor XIV/PROC Protein, Mouse (HEK293, His)
目录号:
HY-P74236
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