Contactin-3/CNTN3 蛋白, Rat (HEK293, His)

Contactin-3/CNTN3 protein mediates crucial cell surface interactions in nervous system development and promotes neurite outgrowth. It interacts with PTPRG, indicating its involvement in signaling mechanisms that regulate neuronal growth and connectivity. Contactin-3/CNTN3 Protein, Rat (HEK293, His) is the recombinant rat-derived Contactin-3/CNTN3 protein, expressed by HEK293 , with C-His labeled tag. The total length of Contactin-3/CNTN3 Protein, Rat (HEK293, His) is 1001 a.a., with molecular weight of 120-150 kDa.

Contactin-3/CNTN3 蛋白参与介导对神经系统发育至关重要的重要细胞表面相互作用。该蛋白还具有促进神经突生长的活性，表明其在促进神经元过程延伸中的作用。此外，Contactin-3/CNTN3 蛋白与 PTPRG 相互作用，表明它参与调节神经元生长和连接的复杂信号传导机制。

Measured by its binding ability in a functional ELISA. When Recombinant Rat CNTN3 is present at 2 μg/mL, can bind Recombinant Human Amyloid Precursor. The ED₅₀ for this effect is 0.098 μg/mL.

Rat

HEK293

C-10*His

Q62682 (E20-G1001)

54279  [NCBI]

ELLLQGPVFVKEPSNSIFPVGSEDKKITLNCEARGNPSPHYRWQLNGSDIDTSLDHRYKLNGGNLIVINPNRNWDTGSYQCFATNSLGTIVSREAKLQFAYLENFKSRMRSRVSVREGQGVVLLCGPPPHSGELSYAWVFNEYPSFVEEDSRRFVSQETGHLYIAKVEPSDVGNYTCVVTSTVTNARVLGSPTPLVLRSDGVMGEYEPKIELQFPETLPAAKGSTVKLECFALGNPVPQINWRRSDGMPFPTKIKLRKFNGVLEIPNFQQEDTGSYECIAENSRGKNVARGRLTYYAKPYWVQLLKDVETAVEDSLYWECRASGKPKPSYRWLKNGDALVLEERIQIENGALTIANLNVSDSGMFQCIAENKHGLIYSSAELKVLASAPDFSRNPMKKMIQVQVGSLVILDCKPSASPRALSFWKKGDTVVREQARISLLNDGGLKIMNVTKADAGIYTCIAENQFGKANGTTQLVVTEPTRIILAPSNMDVAVGESIILPCQVQHDPLLDIMFAWYFNGTLTDFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAAELIVRGSPGPPENVKVDEITDTTAQLSWTEGTDSHSPVISYAVQARTPFSVGWQNVRTVPEAIDGKTRTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAAPEVAPSEVSGGGGSRSELVITWDPVPEELQNGGGFGYVVAFRPLGVTTWIQTVVTSPDNPRYVFRNESIVPFSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSHISAHSLSSSEIEVSWNTIPWKSSNGRLLGYEVRYWNNGGEEESSSKVKVAGNQTSAVLRGLKSNLAYYTAVRAYNTAGAGPFSATVNATTKKTPPSQPPGNVVWNATDTKVLLNWEQVKALENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELLLPIKEDYIIEVKATTDGGDGTSSEQIRIPRITSMDARG

Approximately 120-150 kDa due to the glycosylation.

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.