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  4. CRISP-1 蛋白, Mouse (HEK293, Fc)

CRISP-1 蛋白, Mouse (HEK293, Fc)

目录号: HY-P76292
产品使用指南

CRISP-1蛋白在精子从睾丸过渡到输精管的过程中，在促进精子功能成熟方面发挥着至关重要的作用。它的参与强调了它在控制男性生殖生理学的复杂调节网络中的重要性，强调了当这些细胞穿过生殖道时，它对精子功能和生育力的潜在影响。CRISP-1 蛋白, Mouse (HEK293, Fc) 是重组的 CRISP-1 蛋白，由 HEK293 表达，带有 C-hFc 标签。CRISP-1 蛋白, Mouse (HEK293, Fc) 全长 244 个氨基酸，分子量约为 ~52.4 KDa。

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描述

CRISP-1 protein plays a crucial role in promoting the functional maturation of spermatozoa during their transition from the testis to the ductus deferens. Its involvement underscores its significance in the complex regulatory network governing male reproductive physiology, emphasizing its potential impact on sperm functionality and fertility as these cells navigate through the reproductive tract. CRISP-1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CRISP-1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CRISP-1 Protein, Mouse (HEK293, Fc) is 244 a.a., with molecular weight of ~52.4 KDa.
研究背景

CRISP-1 蛋白参与促进精子从睾丸转移到输精管过程中的功能成熟。这表明 CRISP-1 在与精子发育和成熟相关的复杂过程中发挥着至关重要的作用。当这些细胞穿过生殖道时，CRISP-1被认为在促进必要的变化方面发挥着关键作用，这些变化有助于精子获得功能。CRISP-1 的参与强调了它在控制男性生殖生理学的复杂调控网络中的重要性，强调了它对精子功能和生育能力的潜在影响。
种属

Mouse
表达系统

HEK293
标签

C-hFc
蛋白编号

Q03401 (M1-H244)
基因 ID

11571  [NCBI]
蛋白结构
N-term
CRISP-1 (M1-H244)
Accession # Q03401
hFc
C-term
同用名
Cysteine-rich secretory protein 1; CRISP1; Sperm-coating glycoprotein 1; SCP 1; Aeg-1
分子量

Approximately 52.4 kDa.
纯度

Greater than 85% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

CRISP-1 Protein, Mouse (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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