Decorin/PGS2 蛋白, Rat (HEK293, His)

Decorin/PGS2 protein is involved in regulating extracellular matrix dynamics, affecting the rate of fibril formation and participating in rat cervical dilation. It has versatile binding properties, interacting with type I and type II collagen, fibronectin, and TGF-β, suggesting involvement in a variety of cellular processes. Decorin/PGS2 Protein, Rat (HEK293, His) is the recombinant rat-derived Decorin/PGS2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Decorin/PGS2 Protein, Rat (HEK293, His) is 354 a.a., with molecular weight of ~43 kDa.

核心蛋白聚糖/PGS2 蛋白与影响原纤维形成速率有关，表明其在调节细胞外基质动力学中发挥作用。此外，它可能在大鼠子宫颈扩张中发挥作用。该蛋白质表现出多种结合特征，可与 I 型和 II 型胶原蛋白、纤连蛋白和 TGF-β 相互作用，表明其参与多种细胞过程。此外，核心蛋白聚糖与 MFAP2 和 ELN 形成三元复合物，突显其参与细胞外环境中复杂的分子相互作用。它与 DPT 的相互作用进一步强调了它参与结构和信号成分的调节。对核心蛋白聚糖的功能及其与各种分子伙伴的相互作用的全面探索可以为其在细胞外基质生物学和组织生理学中的多方面作用提供有价值的见解。

Rat

HEK293

C-6*His

Q01129 (G17-K354)

29139  [NCBI]

GPFEQRGLFDFMLEDEASGIIPYDPDNPLISMCPYRCQCHLRVVQCSDLGLDKVPWEFPPDTTLLDLQNNKITEIKEGAFKNLKDLHTLILVNNKISKISPEAFKPLVKLERLYLSKNHLKELPEKLPKTLQELRLHDNEITKLKKSVFNGLNRMIVIELGGNPLKNSGIENGALQGMKGLGYIRISDTNITAIPQGLPTSISELHLDGNKIAKVDAASLKGMSNLSKLGLSFNSITVVENGSLANVPHLRELHLDNNKLLRVPAGLAQHKYVQVVYLHNNNISEVGQHDFCLPSYQTRKTSYTAVSLYSNPVRYWQIHPHTFRCVFGRSTIQLGNYK

Approximately 43 kDa due to the glycosylation

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.