Dermatopontin/DPT 蛋白, Human (HEK293, Fc, His)

Dermatopontin/DPT Protein facilitates adhesion by binding to integrins on the cell surface. It acts as a conduit for communication between dermal fibroblast cells and the extracellular matrix. Furthermore, it enhances TGFB1 activity, inhibits cell proliferation, promotes collagen fibril formation, and stabilizes them at low temperatures. DPT Protein interacts with TGFB1, DCN, and collagen. Dermatopontin/DPT Protein, Human (HEK293, Fc, His) is the recombinant human-derived Dermatopontin/DPT protein, expressed by HEK293 , with C-hFc, C-6*His labeled tag. The total length of Dermatopontin/DPT Protein, Human (HEK293, Fc, His) is 183 a.a., with molecular weight of 50-60 kDa.

皮桥蛋白/DPT 蛋白被认为通过与细胞表面的整合素结合来促进粘附。它可以充当真皮成纤维细胞与其周围细胞外基质之间通讯的管道。此外，它还能增强 TGFB1 的活性，抑制细胞增殖，促进胶原纤维的形成，并有助于稳定胶原纤维在低温下的解离。该蛋白与 TGFB1、DCN 和胶原蛋白相互作用。

Human

HEK293

C-hFc;C-6*His

Q07507 (Q19-V201)

1805  [NCBI]

QYGDYGYPYQQYHDYSDDGWVNLNRQGFSYQCPQGQVIVAVRSIFSKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQTCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWLTTEYPGHYGEEMDMISYNYDYYIRGATTTFSAVERDRQWKFIMCRMTEYDCEFANV

50-60 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 4% Sucrose, 4% mannitol, 0.02% Tween80, pH 7.5.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.