2. 重组蛋白
  3. Receptor Proteins
  4. Cell Adhesion Molecules (CAMs)
  5. Cadherins
  6. Desmocollin-2
  7. DSC2/Desmocollin-2 蛋白, Human (HEK293, His)

DSC2/Desmocollin-2 蛋白, Human (HEK293, His)

目录号: HY-P76301
COA 产品使用指南

DSC2/Desmocollin-2 蛋白对于细胞间桥粒连接至关重要，通过与斑块蛋白和中间丝相互作用来介导粘附。它还调节细胞定位并与 DSP、PKP2 和 JUP 相互作用，增强连接稳定性。总体而言，DSC2/Desmocollin-2 蛋白维持组织组织和功能。DSC2/Desmocollin-2 蛋白, Human (HEK293, His) 是重组的 DSC2/Desmocollin-2 蛋白，由 HEK293 表达，带有 C-His 标签。DSC2/Desmocollin-2 蛋白, Human (HEK293, His) 全长 657 个氨基酸，分子量分别约为 ~85 & 100 KDa。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
5 μg ￥530 In-stock
10 μg ￥900 In-stock
50 μg ￥2500 In-stock
100 μg ￥3800 In-stock
> 100 μg   询价  

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描述

DSC2/Desmocollin-2 protein is vital for intercellular desmosome junctions, mediating adhesion by interacting with plaque proteins and intermediate filaments. It also regulates cell positioning and interacts with DSP, PKP2, and JUP, strengthening junction stability. Overall, DSC2/Desmocollin-2 protein maintains tissue organization and functionality. DSC2/Desmocollin-2 Protein, Human (HEK293, His) is the recombinant human-derived DSC2/Desmocollin-2 protein, expressed by HEK293 , with C-His labeled tag. The total length of DSC2/Desmocollin-2 Protein, Human (HEK293, His) is 657 a.a., with molecular weight of ~85 & 100 KDa, respectively.
研究背景

DSC2/Desmocollin-2 蛋白是细胞间桥粒连接的关键成分，通过介导斑块蛋白和中间丝之间的相互作用，在促进细胞间粘附方面发挥着至关重要的作用。除了其粘附功能外，DSC2 还可能通过调节表达不同亚型的细胞之间的粘附性来促进表皮细胞定位。该蛋白与 DSP、PKP2 和 JUP 相互作用，进一步增强这些连接的稳定性和完整性。通过参与这些分子相互作用，DSC2/Desmocollin-2 蛋白确保组织的正确组织和功能。
种属

Human
表达系统

HEK293
标签

C-His
蛋白编号

Q02487 (A28-R684)
基因 ID
蛋白结构
N-term
DSC2 (A28-R684)
Accession # Q02487
His
C-term
同用名
Cadherin family member 2; CDHF2; DSC3; Desmosomal glycoprotein II
分子量

Approximately 85&100 kDa.
纯度

Greater than 90% as determined by reducing SDS-PAGE.
性状

溶液
组分

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
内毒素含量

<1 EU/μg, determined by LAL method.
复溶方法

N/A.
保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

运输条件

Shipping with dry ice.
文件资料

COA (209 KB)

产品使用指南 (1213 KB)

DSC2/Desmocollin-2 Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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