envelope glycoprotein gp64 蛋白, AcmNPV (sf9, His)

Envelope glycoprotein gp64 is classified as a class III viral fusion protein. As an envelope phosphate glycoprotein, it promotes the fusion of virus and host endosomal membranes, thereby promoting virus entry into host cells. Following receptor-mediated viral internalization, gp64 undergoes a conformational change at low pH into a fusion-competent state, thereby releasing the nucleocapsid into the host cell cytoplasm upon cell fusion. envelope glycoprotein gp64 Protein, AcmNPV (sf9, His) is the recombinant Virus-derived envelope glycoprotein gp64 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of envelope glycoprotein gp64 Protein, AcmNPV (sf9, His) is 481 a.a., with molecular weight of ~54.2 KDa.

包膜糖蛋白 gp64 是一种 III 类病毒融合蛋白，也是某些病毒的关键成分。作为一种包膜磷酸糖蛋白，gp64 在介导病毒与宿主内体膜之间的融合、促进病毒进入宿主细胞方面发挥着关键作用。在受体介导的内化过程中，gp64 在低 pH 条件下发生构象变化，进入可融合状态，从而在细胞融合后将病毒核衣壳释放到细胞质中。此外，gp64 可能参与出芽过程。在结构上，gp64 形成二硫键连接的同源三聚体，有助于其在病毒融合过程中的稳定性和功能性（参考：未提供具体参考）。

Virus

Sf9 insect cells

C-His

P17501 (M1-T481)

1403961  [NCBI]

Approximately 54.2 kDa.

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.