EpCAM/TROP1 蛋白, Mouse (HEK293, Fc)

The EpCAM/TROP1 protein participates in multiple processes, serving as homologous interacting molecules that facilitate communication between mucosal epithelial midgut epithelial cells (IECs) and intraepithelial lymphocytes (IELs). This helps form an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of EpCAM/TROP1 Protein, Mouse (HEK293, Fc) is 243 a.a., with molecular weight of 60-80 kDa.

EpCAM/TROP1 蛋白参与多种生物过程。它可以作为物理同性相互作用分子，促进粘膜上皮中肠上皮细胞（IEC）和上皮内淋巴细胞（IEL）之间的通讯，从而有助于免疫屏障作为抵抗粘膜感染的主要防御。此外，EpCAM/TROP1 在胚胎干细胞的增殖和分化中发挥作用。它还可以上调 FABP5、MYC 以及细胞周期蛋白 A 和 E 的表达，从而可能影响细胞周期进程。EpCAM/TROP1 作为单体存在并与磷酸化的 CLDN7 相互作用。

Mouse

HEK293

C-hFc

Q99JW5 (Q24-T266)

17075  [NCBI]

QRDCVCDNYKLATSCSLNEYGECQCTSYGTQNTVICSKLASKCLAMKAEMTHSKSGRRIKPEGAIQNNDGLYDPDCDEQGLFKAKQCNGTATCWCVNTAGVRRTDKDTEITCSERVRTYWIIIELKHKERESPYDHQSLQTALQEAFTSRYKLNQKFIKNIMYENNVITIDLMQNSSQKTQDDVDIADVAYYFEKDVKGESLFHSSKSMDLRVNGEPLDLDPGQTLIYYVDEKAPEFSMQGLT

60-80 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.