2. 重组蛋白
  3. CAR-T related Proteins CD Antigens
  4. Epithelial Cell Adhesion Molecule (EpCAM) Stem Cell CD Proteins Dendritic Cell CD Proteins Epithelial cell CD Proteins
  5. CD326/EpCAM
  6. EpCAM/TROP1 蛋白, Cynomolgus/Rhesus Macaque (HEK293, Fc)

EpCAM/TROP1 蛋白, Cynomolgus/Rhesus Macaque (HEK293, Fc)

目录号: HY-P75737
产品使用指南

EpCAM/TROP1 蛋白作为均质相互作用分子在多个过程中发挥关键作用，促进粘膜上皮中肠上皮细胞 (IEC) 和上皮内淋巴细胞 (IEL) 之间的通讯，从而建立针对粘膜感染力的免疫力。EpCAM/TROP1 蛋白, Cynomolgus/Rhesus Macaque (HEK293, Fc) 是重组的 EpCAM/TROP1 蛋白，由 HEK293 表达，带有 C-hFc 标签。EpCAM/TROP1 蛋白, Cynomolgus/Rhesus Macaque (HEK293, Fc) 全长 265 个氨基酸，分子量约为 ~58 kDa。

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重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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描述

EpCAM/TROP1 proteins play key roles in multiple processes as homogeneous interacting molecules that facilitate communication between mucosal epithelial midgut epithelial cells (IECs) and intraepithelial lymphocytes (IELs) to establish immunity against mucosal infections force. EpCAM/TROP1 Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of EpCAM/TROP1 Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is 265 a.a., with molecular weight of ~58 kDa.
研究背景

EpCAM/TROP1 蛋白在多种生物过程中发挥着关键作用。它作为一种物理同源相互作用分子，促进粘膜上皮内肠上皮细胞（IEC）和上皮内淋巴细胞（IEL）之间的通讯，从而建立免疫屏障作为抵抗粘膜感染的初始防御。EpCAM/TROP1在调节胚胎干细胞的增殖和分化中也发挥着至关重要的作用。此外，它还参与 FABP5、MYC 以及细胞周期蛋白 A 和 E 的上调，可能影响细胞周期进程。EpCAM/TROP1 作为单体存在，并与磷酸化的 CLDN7 相互作用，进一步凸显其多样化的功能。
种属

Rhesus Macaque
表达系统

HEK293
标签

C-hFc
蛋白编号

Q1WER1 (M1-K265)
基因 ID

677680  [NCBI]
蛋白结构
N-term
EpCAM (M1-K265)
Accession # Q1WER1
hFc
C-term
同用名
Epithelial cell adhesion molecule; Ep-CAM; EGP; KSA; CD326; TROP3
分子量

Approximately 58 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

EpCAM/TROP1 Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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