Ephrin-B1/EFNB1 蛋白, Mouse (HEK293, Fc)

Ephrin-B1 (EFNB1) protein binds to Eph family receptors, enabling signaling between receptor-expressing cells and cells with EFNB1. It is crucial for neuronal axon growth and expressed in various tissues like the adult lung and colon, highlighting its widespread presence and importance in mediating cellular interactions. Ephrin-B1/EFNB1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Ephrin-B1/EFNB1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Ephrin-B1/EFNB1 Protein, Mouse (HEK293, Fc) is 200 a.a., with molecular weight of 55-75 kDa.

Ephrin-B1 (EFNB1) 蛋白由该基因编码，作为 Eph 家族受体的膜配体，促进表达受体的细胞和含有该蛋白的细胞之间的双向信号传导。它对各种发育过程至关重要，其活性在神经元轴突生长中发挥着关键作用。在成人肺和结肠等多种组织中观察到 EFNB1 的广泛表达，强调了它的普遍存在，并强调了它在介导发育期间及以后的重要细胞相互作用中的重要性。

Measured in a cell proliferation assay using HUVEC cells. The ED₅₀ this effect is 7.89 ng/mL, corresponding to a specific activity is 1.267×10⁵ U/mg.

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  Measured in a cell proliferation assay using HUVEC cells. The ED₅₀ this effect is 7.89 ng/mL, corresponding to a specific activity is 1.267×10⁵ U/mg.

Mouse

HEK293

C-hFc

NP_034240.1 (K30-S229)

13641  [NCBI]

KNLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAEAGRPYEYYKLYLVRPEQAAACSTVLDPNVLVTCNKPHQEIRFTIKFQEFSPNYMGLEFKKYHDYYITSTSNGSLEGLENREGGVCRTRTMKIVMKVGQDPNAVTPEQLTTSRPSKESDNTVKTATQAPGRGSQGDSDGKHETVNQEEKSGPGAGGGGSGDS

55-75 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.