EPT1 蛋白, Human (GST)

The EPT1 protein is an ethanolamine phosphotransferase that crucially transfers phosphoethanolamine in the final step of PE synthesis. This process is critical for PE production and involves multiple membrane-related cellular functions. EPT1 Protein, Human (GST) is the recombinant human-derived EPT1 protein, expressed by E. coli , with N-GST labeled tag. The total length of EPT1 Protein, Human (GST) is 50 a.a., with molecular weight of ~29.0 kDa.

EPT1 蛋白充当乙醇胺磷酸转移酶，在 PE 合成的最后一步中通过“Kennedy”途径促进磷酸乙醇胺 (PE) 从 CDP-乙醇胺到脂质受体的关键转移。正如各种研究所阐明的，这种酶促过程对于 PE（哺乳动物细胞膜中第二丰富的磷脂）的生产至关重要，并且复杂地参与多种与膜相关的细胞过程。除了在 PE 合成中的主要作用外，EPT1 在生成各种 PE 物种方面也表现出重要作用，并可能有助于醚连接磷脂的合成，例如血浆酰基 (plasmanyl-) 和血浆酰基 -PE (plasmenyl-PE)。这种双重功能表明它在正确的髓鞘形成和神经发育中发挥着重要作用，强调了 EPT1 对细胞脂质代谢的多方面贡献。

Human

E. coli

N-GST

Q9C0D9 (M1-P50)

85465  [NCBI]

MAGYEYVSPEQLAGFDKYKYSAVDTNPLSLYVMHPFWNTIVKVFPTWLAP

Approximately 29.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.