FAM3B 蛋白, Human (206a.a, HEK293, Fc)

FAM3B Protein acts as a potent inducer of apoptosis, influencing alpha and beta cells in a dose- and time-dependent manner. Its regulatory impact on programmed cell death underscores its significance, particularly within apoptosis. The specificity for alpha and beta cells suggests targeted modulation of pancreatic cell populations, implicating FAM3B in key processes related to pancreatic function and homeostasis. FAM3B Protein, Human (206a.a, HEK293, Fc) is the recombinant human-derived FAM3B protein, expressed by HEK293 , with C-hFc labeled tag. The total length of FAM3B Protein, Human (206a.a, HEK293, Fc) is 206 a.a., with molecular weight of 50-65 kDa.

FAM3B 蛋白是细胞凋亡的有效诱导剂，以剂量和时间依赖性方式作用于 α 和 β 细胞。它对程序性细胞死亡的调节影响凸显了它在塑造细胞反应中的重要性，特别是在细胞凋亡的背景下。这种作用对 α 和 β 细胞的特异性表明对胰腺细胞群有针对性的影响，可能表明 FAM3B 参与了与胰腺功能和稳态相关的关键过程的调节。

Human

HEK293

C-hFc

P58499 (E30-S235)

54097  [NCBI]

ELIPDAPLSSAAYSIRSIGERPVLKAPVPKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKERS

50-65 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.