1. 重组蛋白
  2. CD Antigens Fc Receptors
  3. Macrophage CD Proteins Monocyte CD Proteins Platelet CD Proteins Dendritic Cell CD Proteins Fc-gamma Receptor
  4. Fc gamma RII/CD32 FCGR2A/CD32a
  5. FCGR2A/CD32a
  6. Fc gamma RIIA/CD32a 蛋白, Rat (HEK293, Fc)

Fc gamma RIIA/CD32a 蛋白, Rat (HEK293, Fc)

目录号: HY-P76233
产品使用指南

Fc gamma RIIA/CD32a 蛋白对于免疫球蛋白受体结合至关重要。它调节吞噬作用过程中的 Fc-γ 受体信号传导、抗体依赖性细胞毒性和肿瘤坏死因子产生等过程。Fc gamma RIIA/CD32a 蛋白, Rat (HEK293, Fc) 是重组的 Fc gamma RIIA/CD32a 蛋白,由 HEK293 表达,带有 C-hFc 标签。Fc gamma RIIA/CD32a 蛋白, Rat (HEK293, Fc) 全长 185 个氨基酸,分子量约为 ~47.5 KDa。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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描述

The Fc gamma RIIA/CD32a protein is essential for immunoglobulin receptor binding. It regulates processes such as Fc-γ receptor signaling during phagocytosis, antibody-dependent cellular cytotoxicity, and tumor necrosis factor production. Fc gamma RIIA/CD32a Protein, Rat (HEK293, Fc) is the recombinant rat-derived Fc gamma RIIA/CD32a protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Fc gamma RIIA/CD32a Protein, Rat (HEK293, Fc) is 185 a.a., with molecular weight of ~47.5 KDa.

研究背景

Fc gamma RIIA/CD32a 蛋白在实现免疫球蛋白受体结合活性方面发挥着至关重要的作用。它参与多种过程,例如调节参与吞噬作用的 Fc-gamma 受体信号通路、抗体依赖性细胞毒性和肿瘤坏死因子的产生。这种蛋白质位于细胞表面,已用于新月体肾小球肾炎的研究。该基因的人类直系同源物 FCGR2A 与多种疾病有关,包括自身免疫性疾病、登革热疾病、血液癌症、白细胞减少症和疟疾。它在多个组织中表现出偏向表达,其中在肺和脾等组织中表达水平显着。该信息由基因组资源联盟截至 2022 年 4 月提供。

种属

Rat

表达系统

HEK293

标签

C-hFc

蛋白编号

NP_446295 (D32-L216)

基因 ID

116591  [NCBI]

蛋白结构
N-term
CD32a (D32-L216)
Accession # NP_446295
hFc
C-term
同用名
FCGR2A; CD32; CD32A; CDw32; IGFR2; fcRII-a; fc-gamma-RIIa; FCG2; FcGR; FCGR2; FCGR2A1; MGC23887; MGC30032
分子量

Approximately 47.5 kDa.

纯度

Greater than 85% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Fc gamma RIIA/CD32a Protein, Rat (HEK293, Fc)
目录号:
HY-P76233
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