Ferritin heavy chain/FTH1 蛋白, Human

The ferritin heavy chain/FTH1 protein is critical for maintaining iron homeostasis, storing iron in soluble form through ferroxidase activity. It promotes the oxidation of ferrous iron so that it can be deposited in the form of iron hydroxide. Ferritin heavy chain/FTH1 Protein, Human is the recombinant human-derived Ferritin heavy chain/FTH1 protein, expressed by E. coli , with tag free. The total length of Ferritin heavy chain/FTH1 Protein, Human is 183 a.a., with molecular weight of ~22.34 kDa.

铁蛋白重链/FTH1 蛋白通过以可溶且无毒的形式储存铁，在铁稳态中发挥着至关重要的作用。具有亚铁氧化酶活性，可促进亚铁的氧化，使其以氢氧化铁的形式沉积。除了储存铁之外，这种蛋白质还有助于将铁输送到细胞，强调其多方面的功能。此外，FTH1 参与介导肾脏发育过程中胶囊细胞的铁吸收，进一步凸显了其在各种生理过程中的重要性。

Data is not available.

Human

E. coli

Tag Free

P02794 (M1-S183)

2495  [NCBI]

MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDNES

Approximately 22.34 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.