1. 重组蛋白
  2. Cytokines and Growth Factors
  3. FGF Family
  4. Fibroblast Growth Factor
  5. FGF-1
  6. FGF-1 蛋白, Rat

FGF-1 蛋白, Rat 是重组大鼠来源的 FGF-1 蛋白,由 E. coli 表达,不带标签。

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SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

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描述

FGF-1 Protein, Rat is the recombinant rat-derived FGF-1 protein, expressed by E. coli, with tag free tag.

研究背景

FGF-1 蛋白在调节细胞存活、分裂、血管生成、分化和迁移等重要细胞过程中发挥着关键作用。在体外,它表现出有效的有丝分裂特性,并可作为 FGFR1 和整合素的配体。当存在肝素时,FGF-1 与 FGFR1 结合,通过酪氨酸残基的自磷酸化导致 FGFR1 的二聚化和激活。这些磷酸化残基充当相互作用蛋白质的对接位点,启动各种信号级联反应。FGF-1 还与整合素结合,并与整合素和 FGFR1 形成三元复合物,这对于 FGF-1 信号转导至关重要。

种属

Rat

表达系统

E. coli

标签

Tag Free

蛋白编号

P61149 (M1-D155)

基因 ID

25317

蛋白结构
N-term
FGF-1 (M1-D155)
Accession # P61149
C-term
同用名
Fibroblast growth factor 1; HBGF-1;  FGF1;  FGF-a;  FGF-acidic
氨基酸序列

MFNLPLGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESAGEVYIKGTETGQYLAMDTEGLLYGSQTPNEECLFLERLEENHYNTYTSKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD

预测分子量
15.9 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
FGF-1 Protein, Rat
目录号:
HY-P704537
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