1. 重组蛋白
  2. Cytokines and Growth Factors
  3. FGF Family
  4. Fibroblast Growth Factor
  5. FGF-2/bFGF
  6. FGF2 蛋白, Chicken (N-His, C-Myc)

FGF2 蛋白, Chicken (N-His, C-Myc)

目录号: HY-P700487
产品使用指南

FGF2 蛋白充当 FGFR1-4 的配体和 FGF2 信号传导的整合素配体。它调节细胞的存活、分裂、分化和迁移。FGF2 蛋白是一种强有丝分裂原,可以诱导血管生成。FGF2 蛋白, Chicken (N-His, C-Myc) 是重组的 FGF2 蛋白,由 E. coli 表达,带有 C-Myc, N-10*His 标签。FGF2 蛋白, Chicken (N-His, C-Myc) 全长 146 个氨基酸,分子量为 23.8 kDa。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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描述

FGF2 Protein acts as a ligand for FGFR1-4 and an integrin ligand for FGF2 signaling. It regulates cell survival, division, differentiation, and migration. FGF2 Protein is a strong mitogen and can induce angiogenesis. FGF2 Protein, Chicken (N-His, C-Myc) is the recombinant FGF2 protein, expressed by E. coli, with C-Myc, N-10*His labeled tag. The total length of FGF2 Protein, Chicken (N-His, C-Myc) is 146 a.a., with molecular weight of 23.8 kDa.

研究背景

FGF2 蛋白充当 FGFR1、FGFR2、FGFR3 和 FGFR4 的配体,以及 FGF2 信号转导必需的整合素配体。它在调节细胞存活、分裂、分化和迁移中起着至关重要的作用。此外,FGF2 在体外可作为有效的有丝分裂原,并具有诱导血管生成的能力。

种属

Others

表达系统

E. coli

标签

C-Myc;N-10*His

蛋白编号

P48800 (P13-S158)

基因 ID

396413  [NCBI]

蛋白结构
N-term
10*His
FGF2 (P13-S158)
Accession # P48800
Myc
C-term
同用名
Fibroblast Growth Factor 2; FGF-2; Basic Fibroblast Growth Factor; bFGF; Heparin-Binding Growth Factor 2; HBGF-2; Fgf2; Fgf-2
氨基酸序列

PALPDDGGGGAFPPGHFKDPKRLYCKNGGFFLRINPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVSANRFLAMKEDGRLLALKCATEECFFFERLESNNYNTYRSRKYSDWYVALKRTGQYKPGPKTGPGQKAILFLPMSAKS

分子量

23.8 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

FGF2 Protein, Chicken (N-His, C-Myc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
FGF2 Protein, Chicken (N-His, C-Myc)
目录号:
HY-P700487
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