2. 重组蛋白
  3. Cytokines and Growth Factors
  4. FLT3LG 蛋白, Human (Tag Free)

FLT3LG 蛋白, Human (Tag Free)

目录号: HY-P700072
产品使用指南

FLT3LG Proteinas 是一种早期造血细胞增殖的有效刺激剂，可激活 FLT3 并与集落刺激因子和白细胞介素产生协同作用。作为同型二聚体，尤其是同工型 2，它对促进造血祖细胞的扩增和分化至关重要。FLT3LG 与其他分子的协同信号强调了其在调节造血和维持造血系统平衡方面的重要性。FLT3LG 蛋白, Human (Tag Free) 是重组的 FLT3LG 蛋白，由 E. coli 表达，不带标签。FLT3LG 蛋白, Human (Tag Free) 全长 155 个氨基酸，分子量约为 ~17.61 kDa。

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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描述

FLT3LG Proteinas, a potent stimulator of early hematopoietic cell proliferation, activates FLT3 and synergizes with colony-stimulating factors and interleukins. As a homodimer, especially in isoform 2, it crucially promotes expansion and differentiation of hematopoietic progenitor cells. FLT3LG's collaborative signaling with other molecules underscores its significance in regulating hematopoiesis and maintaining hematopoietic system balance. FLT3LG Protein, Human (Tag Free) is the recombinant human-derived FLT3LG protein, expressed by E. coli, with tag free. The total length of FLT3LG Protein, Human (Tag Free) is 155 a.a., with molecular weight of ~17.61 kDa.
研究背景

FLT3LG 蛋白通过激活 FLT3 作为早期造血细胞增殖的有效刺激剂，与各种集落刺激因子和白细胞介素结合时显示出协同效应。这种同型二聚体蛋白，尤其是亚型 2，在促进造血祖细胞的扩增和分化中发挥着至关重要的作用。它激活FLT3并与其他信号分子协作的能力强调了其在调节造血和维持造血系统平衡方面的重要性。
种属

Human
表达系统

E. coli
标签

Tag Free
蛋白编号

P49771-1 (T27-A181)
基因 ID

2323
蛋白结构
N-term
FLT3LG (T27-A181)
Accession # P49771-1
C-term
同用名
Flt-3 Ligand; Flt3 ligand; FL; SL cytokine; Flt-3L
氨基酸序列

TQDCSFQHSPISSDFAVKIRELSDYLLQDYPVTVASNLQDEELCGGLWRLVLAQRWMERLKTVAGSKMQGLLERVNTEIHFVTKCAFQPPPSCLRFVQTNISRLLQETSEQLVALKPWITRQNFSRCLELQCQPDSSTLPPPWSPRPLEATAPTA

分子量

Approximately 17.61 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

< 1 EU/μg of protein by gel clotting method
文件资料
产品使用指南 (1213 KB)

FLT3LG Protein, Human (Tag Free) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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