FLT3LG 蛋白, Mouse (HEK293, His)

FLT3LG Proteinas, a potent stimulator, activates FLT3, synergizing with colony-stimulating factors and interleukins. Its homodimeric form, especially in the soluble isoform, effectively promotes the expansion and differentiation of hematopoietic progenitor cells. The protein's significance lies in orchestrating key processes within the hematopoietic system. FLT3LG Protein, Mouse (HEK293, His) is the recombinant mouse-derived FLT3LG protein, expressed by HEK293 , with C-6*His labeled tag. The total length of FLT3LG Protein, Mouse (HEK293, His) is 162 a.a., with molecular weight of ~22-33 kDa.

FLT3LG 蛋白充当有效的刺激剂，通过激活 FLT3 促进早期造血细胞的增殖。这种同型二聚体蛋白表现出协同效应，特别是在其可溶性异构体中，可与各种集落刺激因子和白细胞介素有效地协同作用。它在促进造血祖细胞扩增和分化方面的作用强调了它在协调造血系统内关键过程中的重要性。

Measured in a cell proliferation assay using K562 cells. The ED₅₀ this effect is 4.628 ng/mL, corresponding to a specific activity is 2.1608×10⁵ units/mg.

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  Measured in a cell proliferation assay using K562 cells. The ED₅₀ this effect is 4.628 ng/mL, corresponding to a specific activity is 2.1608×10⁵ units/mg.

Mouse

HEK293

C-6*His

P49772 (G27-R188)

14256  [NCBI]

GTPDCYFSHSPISSNFKVKFRELTDHLLKDYPVTVAVNLQDEKHCKALWSLFLAQRWIEQLKTVAGSKMQTLLEDVNTEIHFVTSCTFQPLPECLRFVQTNISHLLKDTCTQLLALKPCIGKACQNFSRCLEVQCQPDSSTLLPPRSPIALEATELPEPRPR

Approximately 22-33 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.