1. 重组蛋白
  2. Cytokines and Growth Factors
  3. FLT3LG 蛋白, Rat (sf9, His)

FLT3LG 蛋白, Rat (sf9, His)

目录号: HY-P74150
产品使用指南

FLT3LG 蛋白具有相同的蛋白结合和受体酪氨酸激酶结合活性,预计可积极调节自然杀伤细胞增殖。它位于细胞表面和细胞外空间,作为质膜外部的内在成分。FLT3LG 蛋白, Rat (sf9, His) 是重组的 FLT3LG 蛋白,由 Sf9 insect cells 表达,带有 C-His 标签。FLT3LG 蛋白, Rat (sf9, His) 全长 162 个氨基酸,分子量约为 ~19.7 kDa。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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描述

The FLT3LG protein has the same protein-binding and receptor tyrosine kinase-binding activities predicted to positively regulate natural killer cell proliferation. Intended to be located on the cell surface and extracellular space, it serves as an intrinsic component on the outside of the plasma membrane. FLT3LG Protein, Rat (sf9, His) is the recombinant rat-derived FLT3LG protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of FLT3LG Protein, Rat (sf9, His) is 162 a.a., with molecular weight of ~19.7 kDa.

研究背景

FLT3LG 蛋白预计具有相同的蛋白结合活性和受体酪氨酸激酶结合活性。它在自然杀伤细胞增殖的正向调节中发挥作用,预计位于细胞表面和细胞外空间,作为质膜外侧的内在成分。这种蛋白质已被用于胰腺癌的研究。在人类疾病中,该基因的直系同源物与结肠癌、胶质母细胞瘤和高级别胶质瘤有关。FLT3LG 基因与人类 FLT3LG 基因(fms 相关受体酪氨酸激酶 3 配体)是直系同源的。[基因组资源联盟提供,2022 年 4 月]

种属

Rat

表达系统

Sf9 insect cells

标签

C-His

蛋白编号

NP_001292868 (T28-Q189)

基因 ID

103691134  [NCBI]

蛋白结构
N-term
FLT3LG (T28-Q189)
Accession # NP_001292868
His
C-term
同用名
Fms-related tyrosine kinase 3 ligand; Flt3 Ligand; Flt3L; SL Cytokine; FLT3LG
分子量

Approximately 19.7 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

FLT3LG Protein, Rat (sf9, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
FLT3LG Protein, Rat (sf9, His)
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HY-P74150
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