FSH beta 蛋白, Mouse (HEK293, Fc)

FSH beta together with the alpha chain CGA form follicle-stimulating hormone or follicle-stimulating hormone (FSH), thus conferring biological specificity. FSH beta binds to FSHR on target cells, initiating key signaling pathways critical for follicle development and spermatogenesis. FSH beta Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived FSH beta protein, expressed by HEK293 , with C-hFc labeled tag. The total length of FSH beta Protein, Mouse (HEK293, Fc) is 111 a.a., with molecular weight of 50-60 kDa.

FSH β 蛋白与 α 链 CGA 结合形成促卵泡素，也称为卵泡刺激素 (FSH)，赋予激素异二聚体生物特异性。FSH beta 与 FSHR（靶细胞上的一种 G 蛋白偶联受体）结合，启动下游信号传导通路。这种激素在生殖器官内的卵泡发育和精子发生中起着关键作用。在结构上，活性促卵泡素是一种异二聚体，由与其他激素共享的 α 链/CGA 和独特的 β 链/FSHB 组成。FSH β 在激素异二聚体中的复杂组装强调了其对生殖过程和激素信号级联的重要贡献。

Mouse

HEK293

C-hFc

Q60687 (H20-E130)

14308  [NCBI]

50-60 kDa

Greater than 95% as determined by Tris-Bis PAGE.

无菌粉末.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.