FtsZ 蛋白, E.coli (His-SUMO)

FtsZ is an essential cell division protein that plays a central role in coordinating the formation of the contractile Z ring at the site of expected cell division. Precise regulation of the components of this ring is a key determinant, affecting the timing and location of cell division. FtsZ Protein, E.coli (His-SUMO) is the recombinant E. coli-derived FtsZ protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag. The total length of FtsZ Protein, E.coli (His-SUMO) is 383 a.a., with molecular weight of ~56.3 kDa.

FtsZ（丝状温度敏感突变体Z）蛋白是细胞分裂中不可缺少的成分，在未来细胞分裂部位的收缩环结构（称为Z环）的形成中发挥着核心作用。该环的组装对于调节细胞分裂的时间和位置至关重要。从功能上讲，FtsZ 环用于将各种其他细胞分裂蛋白募集到隔膜，促进分裂细胞之间新细胞壁的合成。作为一种具有内在 GTP 酶活性的 GTP 结合蛋白，FtsZ 以同二聚体形式存在，并以严格依赖 GTP 的方式聚合形成动态环结构。这种与 GTP 的动态相互作用及其形成 Z 环的能力是基本特征，突出了 FtsZ 在协调细菌细胞分裂的复杂过程中的关键作用。此外，FtsZ 直接与其他几种分裂蛋白相互作用，强调其在协调成功细胞分裂所需的分子事件中的核心作用（参考：提供的信息）。

E.coli

E. coli

N-SUMO;N-6*His

P0A9A7 (M1-D383)

58460765  [NCBI]

MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNTDAQALRKTAVGQTIQIGSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAAGMGGGTGTGAAPVVAEVAKDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSLITIPNDKLLKVLGRGISLLDAFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMSEMGYAMMGSGVASGEDRAEEAAEMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFETVGNTIRAFASDNATVVIGTSLDPDMNDELRVTVVATGIGMDKRPEITLVTNKQVQQPVMDRYQQHGMAPLTQEQKPVAKVVNDNAPQTAKEPDYLDIPAFLRKQAD

Approximately 56.3 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm sterile filtered PBS, 6% Trehalose, pH 7.4

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.