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  3. Growth Hormone R/GHR 蛋白, Mouse (HEK293, Fc)

Growth Hormone R/GHR 蛋白, Mouse (HEK293, Fc)

目录号: HY-P70850
COA 产品使用指南

生长激素 R/GHR 蛋白,尤其是其可溶形式 GHBP,可充当生长激素的血浆储存库。GHBP 不仅调节生长激素的可用性,还可能调节或抑制生长激素信号传导。这种双重作用凸显了 GHBP 对与循环系统中生长激素活性相关的复杂信号通路的调节影响。Growth Hormone R/GHR 蛋白, Mouse (HEK293, Fc) 是重组的 生长激素 R/GHR 蛋白,由 HEK293 表达,带有 C-hFc 标签。Growth Hormone R/GHR 蛋白, Mouse (HEK293, Fc) 全长 273 个氨基酸,分子量为 65-90 kDa。

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规格 价格 是否有货 数量
10 μg ¥890 In-stock
50 μg ¥2500 In-stock
100 μg   询价  

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描述

Growth Hormone R/GHR Protein, especially in its soluble form GHBP, acts as a plasma reservoir for growth hormone. GHBP not only regulates growth hormone availability but also potentially modulates or inhibits growth hormone signaling. This dual role highlights GHBP's regulatory impact on the intricate signaling pathways associated with growth hormone activity in the circulatory system. Growth Hormone R/GHR Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Growth Hormone R/GHR protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Growth Hormone R/GHR Protein, Mouse (HEK293, Fc) is 273 a.a., with molecular weight of 65-90 kDa.

研究背景

生长激素 R/GHR 蛋白,特别是其可溶形式的 GHBP,可作为血浆中生长激素的储存库。这种可溶性变体还具有潜在调节或抑制生长激素信号传导的额外作用。通过充当储存库,GHBP 有助于循环系统中生长激素的调节和利用,其调节或抑制功能表明在与生长激素活性相关的复杂信号通路中具有调节作用。

种属

Mouse

表达系统

HEK293

标签

C-hFc

蛋白编号

Q3UP14 (M1-Q273)

基因 ID

14600  [NCBI]

蛋白结构
N-term
GHR (M1-Q273)
Accession # Q3UP14
hFc
C-term
同用名
growth hormone binding protein; growth hormone receptor; serum binding protein; Somatotropin receptor; GHR; GH receptor; GHBP
氨基酸序列

MDLCQVFLTLALAVTSSTFSGSEATPATLGKASPVLQRINPSLGTSSSGKPRFTKCRSPELETFSCYWTEGDNPDLKTPGSIQLYYAKRESQRQAARIAHEWTQEWKECPDYVSAGKNSCYFNSSYTSIWIPYCIKLTTNGDLLDQKCFTVDEIVQPDPPIGLNWTLLNISLTGIRGDIQVSWQPPPNADVLKGWIILEYEIQYKEVNESKWKVMGPIWLTYCPVYSLRMDKEHEVRVRSRQRSFEKYSEFSEVLRVIFPQTNILEACEEDIQ

分子量

65-90 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

性状

无菌粉末.

组分

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US;may vary elsewhere.

文件资料

Growth Hormone R/GHR Protein, Mouse (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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