GIPR 蛋白, Mouse (HEK293, His)

AK2 protein plays a key role in cellular energy homeostasis and adenine nucleotide metabolism by catalyzing the reversible transfer of terminal phosphate groups between ATP and AMP. Its adenylate kinase activity plays a key role in regulating phosphate utilization and de novo AMP biosynthetic pathways, contributing to the complex balance of cellular energy resources. GIPR Protein, Mouse (HEK293, His) is the recombinant mouse-derived GIPR, expressed by HEK293, with C-10*His labeled tag. The total length of GIPR Protein, Mouse (HEK293, His) is 116 a.a..

GIPR 蛋白作为葡萄糖依赖性促胰岛素多肽 (GIP) 的受体发挥作用。其活性由 G 蛋白介导，特别是那些激活腺苷酸环化酶的蛋白。值得注意的是，GIPR 有可能与 GLP1R 形成同二聚体和异二聚体，这表明与肠促胰岛素激素相关的受体之间可能存在相互作用。

Measured by its binding ability in a functional ELISA. Immobilized GIPR, Mouse (HEK293, His) at 2 μg/mL can bind Anti-Mouse Gipr Recombinant Antibody, the EC₅₀ is ≤30 ng/mL.

• 
  Measured by its binding ability in a functional ELISA. Immobilized GIPR, Mouse (HEK293, His) at 2 μg/mL can bind Anti-Mouse Gipr Recombinant Antibody, the EC₅₀ is 25.62 ng/mL.

Mouse

HEK293

C-10*His

Q0P543-1 (E19-Q134)

381853

Extracellular Domain

Approximately 19-33 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

1.Lyophilized from a 0.22 μm filtered solution of 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0.
2.Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4, 6% Trehalose.
3.Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4, 8% Trehalose.
Please refer to the lot-specific COA for specific buffer information.
Note: For SPR assay, please replace the buffer. Primary amine components (e.g., Tris, imidazole) can affect protein-coupled chips.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.