1. 重组蛋白
  2. Viral Proteins
  3. glycoprotein G/gG 蛋白, HHV-1 (Cell-Free, His)

glycoprotein G/gG 蛋白, HHV-1 (Cell-Free, His)

目录号: HY-P702297
产品使用指南

糖蛋白 G/gG 蛋白作为趋化因子结合蛋白,通过抑制中性粒细胞趋化性来关键调节免疫反应。它可以防止中性粒细胞响应趋化因子信号而迁移,有助于对组织内免疫细胞的招募和定位进行微调控制。这凸显了该蛋白质在协调免疫系统和维持免疫稳态方面的重要性。glycoprotein G/gG 蛋白, HHV-1 (Cell-Free, His) 是重组的 糖蛋白 G/gG 蛋白,由 E. coli Cell-free 表达,带有 N-10*His 标签。glycoprotein G/gG 蛋白, HHV-1 (Cell-Free, His) 全长 214 个氨基酸,分子量为 28.8 kDa。

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描述

The glycoprotein G/gG protein, functioning as a chemokine-binding protein, critically modulates immune responses by inhibiting neutrophil chemotaxis. It prevents the migration of neutrophils in response to chemokine signals, contributing to the fine-tuned control of immune cell recruitment and positioning within tissues. This highlights the protein's significance in orchestrating the immune system and maintaining immune homeostasis. glycoprotein G/gG Protein, HHV-1 (Cell-Free, His) is the recombinant Virus-derived glycoprotein G/gG protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of glycoprotein G/gG Protein, HHV-1 (Cell-Free, His) is 214 a.a., with molecular weight of 28.8 kDa.

研究背景

糖蛋白G/gG蛋白作为趋化因子结合蛋白,通过抑制中性粒细胞的趋化性发挥其功能。这种蛋白质在调节中性粒细胞的运动、防止中性粒细胞响应趋化因子信号而迁移方面发挥着关键作用。通过充当中性粒细胞趋化性的调节剂,糖蛋白 G/gG 有助于免疫反应的微调控制,影响组织内免疫细胞的募集和定位。这种对中性粒细胞趋化性的抑制凸显了该蛋白质在免疫系统复杂协调中的重要性及其在维持免疫稳态中的潜在作用。

种属

Virus

表达系统

E. coli Cell-free

标签

N-10*His

蛋白编号

P06484 (V25-G238)

基因 ID

2703404

蛋白结构
N-term
10*His
HHV-2 gG (V25-G238)
Accession # P06484
C-term
同用名
Envelope glycoprotein G; gG-1
氨基酸序列

VPTNVSSTTQPQLQTTGRPSHEAPNMTQTGTTDSPTAISLTTPDHTPPMPSIGLEEEEEEEGAGDGEHLEGGDGTRDTLPQSPGPAFPLAEDVEKDKPNRPVVPSPDPNNSPARPETSRPKTPPTIIGPLATRPTTRLTSKGRPLVPTPQHTPLFSFLTASPALDTLFVVSTVIHTLSFLCIGAMATHLCGGWSRRGRRTHPSVRYVCLPSERG

分子量

28.8 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

glycoprotein G/gG Protein, HHV-1 (Cell-Free, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
glycoprotein G/gG Protein, HHV-1 (Cell-Free, His)
目录号:
HY-P702297
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