1. 重组蛋白
  2. Cytokines and Growth Factors GMP-grade Proteins
  3. FGF Family
  4. Fibroblast Growth Factor
  5. Fibroblast Growth Factor 7 (FGF-7)
  6. GMP KGF/FGF-7 蛋白, Human (163a.a)

GMP KGF/FGF-7 蛋白, Human (163a.a)

目录号: HY-P70597G
COA 产品使用指南

KGF/FGF-7 蛋白协调胚胎发育,调节细胞增殖和分化等基本过程。它的关键作用延伸到正常的分支形态发生。作为角质形成细胞的生长因子,KGF/FGF-7 控制上皮细胞增殖。与 FGFBP1 和 FGFR2 的关键相互作用,以及通过硫酸乙酰肝素糖胺聚糖增强的结合亲和力,强调了 KGF/FGF-7 作为旁分泌效应器在胚胎发育过程中分子相互作用中的关键作用。GMP KGF/FGF-7 蛋白, Human (163a.a) 是重组的 GMP 级别 KGF/FGF-7 蛋白,由 E. coli 表达,不带标签。GMP KGF/FGF-7 蛋白, Human (163a.a) 全长 163 个氨基酸,分子量为 15-18 kDa。

GMP 级别 (GMP-grade) 重组蛋白是在独立的 QA 监督下生产,并具有质量记录和完全可追溯性。

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重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg 询价

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描述

KGF/FGF-7 Protein orchestrates embryonic development, regulating fundamental processes like cell proliferation and differentiation. Its pivotal role extends to normal branching morphogenesis. As a growth factor for keratinocytes, KGF/FGF-7 governs epithelial cell proliferation. Key interactions with FGFBP1 and FGFR2, along with heightened binding affinity through heparan sulfate glycosaminoglycans, underscore KGF/FGF-7's crucial role as a paracrine effector in molecular interactions during embryonic development. GMP KGF/FGF-7 Protein, Human (163a.a) is the recombinant human-derived KGF/FGF-7 protein, expressed by E. coli, with tag free. The total length of GMP KGF/FGF-7 Protein, Human (163a.a) is 163 a.a., with molecular weight of 15-18 kDa.

研究背景

KGF/FGF-7 蛋白在协调胚胎发育中发挥着至关重要的作用,对细胞增殖和分化等基本过程具有调节控制作用。它的重要贡献延伸到正常分支形态发生的复杂领域,其中 KGF/FGF-7 发挥着关键作用。作为一种对角质形成细胞具有特异性活性的生长因子,它是控制正常上皮细胞增殖的潜在主要旁分泌效应物。该蛋白建立了关键的相互作用,与 FGFBP1 和 FGFR2 形成复合物,并且其与成纤维细胞生长因子 (FGF) 及其受体的结合亲和力通过硫酸乙酰肝素糖胺聚糖增强,在这些分子相互作用中充当关键的辅助受体。

种属

Human

表达系统

E. coli

标签

Tag Free

蛋白编号

P21781 (C32-T194)

基因 ID

2252

蛋白结构
N-term
FGF-7 (C32-T194)
Accession # P21781
C-term
中文名
GMP级重组人KGF蛋白
同用名
Fibroblast growth factor 7; FGF-7; Heparin-binding growth factor 7; HBGF-7; Keratinocyte growth factor; FGF7; KGF
分子量

15-18 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
GMP KGF/FGF-7 Protein, Human (163a.a)
目录号:
HY-P70597G
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