GPR87 Protein-VLP, Human (HEK293)

GPR87, a lysophosphatidic acid (LPA) receptor, crucially activates p53/TP53-dependent survival pathways in response to DNA damage. Its interaction with LPA plays a key role in mediating cellular responses to DNA damage, highlighting its significance in cell survival and DNA damage repair processes. GPR87 Protein-VLP, Human (HEK293) is the recombinant human-derived GPR87 protein, expressed by HEK293, with tag free.Formed in HEK293 cultures, these VLPs concentrate membrane proteins on the cell surface, producing high-concentration proteins ideal for immunization and antibody screening. Given the high immunogenicity of VLPs, the immunization protocol such as antigen dose, schedule, and adjuvant, requires optimization. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays. If VLP control is required, it is recommended HY-P705433.

GPR87 是溶血磷脂酸 (LPA) 的受体，在响应 DNA 损伤而激活的 p53/TP53 依赖性生存途径中发挥着至关重要的作用。该受体与 LPA 的结合有助于介导细胞对 DNA 损伤的反应，强调了其在与细胞存活和 DNA 损伤修复相关的过程中的重要性。

Human

HEK293

Tag Free

Q9BY21 (M1-V358)

53836

Full Length

溶液

Supplied as 0.2 μm filtered solution in PBS, Arginine, pH7.4 with trehalose as protectant.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.