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  4. Hamster FGF21 Protein 蛋白, Hamster (HEK293, His)

Hamster FGF21 Protein 蛋白, Hamster (HEK293, His)

目录号: HY-P703749
产品使用指南 技术支持

FGF21 是一种肝因子，通过下丘脑室旁核的 FGF21 受体发出信号，调节单糖的摄入和对甜食的偏好。FGF21 通过激活 SIRT1/PI3K/AKT 信号通路促进非小细胞肺癌进展。FGF21 对胚胎发育、细胞生长、形态发生、组织修复、肿瘤生长和侵袭有重要作用。Hamster FGF21 Protein 蛋白, Hamster (HEK293, His) 是重组的 Hamster FGF21 Protein 蛋白，由 HEK293 表达，带有 C-His 标签。

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规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

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描述

FGF21 is a liver factor that signals through the FGF21 receptor in the paraventricular nucleus of the hypothalamus to regulate monosaccharide intake and preference for sweets. FGF21 promotes the progression of non-small cell lung cancer by activating the SIRT1/PI3K/AKT signaling pathway. FGF21 plays an important role in embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. Hamster FGF21 Protein Protein, Hamster (HEK293, His) is the recombinant 0-derived Hamster FGF21 Protein protein, expressed by HEK293, with C-His labeled tag.
研究背景

成纤维细胞生长因子 21 是成纤维细胞生长因子 (FGF) 家族的成员。FGF 家族成员具有广泛的有丝分裂和细胞存活活性，参与多种生物学过程，包括胚胎发育、细胞生长、形态发生、组织修复、肿瘤生长和侵袭。FGF21 是一种肝因子，即肝脏分泌的一种激素，通过下丘脑室旁核的 FGF21 受体发出信号，调节单糖的摄入和对甜食的偏好，并与伏隔核内多巴胺神经传递减少有关。FGF21 通过激活 SIRT1/PI3K/AKT 信号通路促进非小细胞肺癌进展。
表达系统

HEK293
标签

C-His
蛋白编号

XP_005084765 (R29-S209)
蛋白长度

Partial
中文名
Hamster 成纤维细胞生长因子21 蛋白
预测分子量
20.8 kDa
分子量

Approximately 21-30 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
纯度

Greater than 95% as determined by reducing SDS-PAGE.；> 90% as determined by HPLC
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

Hamster FGF21 Protein Protein, Hamster (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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