Haptoglobin 蛋白, Rat (HEK293, His)

Haptoglobin Proteinas, a positive regulator of collagen fibrillogenesis, likely plays a crucial role in extracellular matrix organization and remodeling. Its involvement extends to positively regulating MAP-kinase activity, contributing to increased adipocyte proliferation and diminished differentiation. Haptoglobin may also serve as a positive regulator of NF-kappa-B activity in macrophages, enhancing inflammatory responsiveness. Additionally, it exhibits transcriptional repressor activity, suggesting its role in gene expression modulation. Haptoglobin Protein, Rat (HEK293, His) is the recombinant rat-derived Haptoglobin protein, expressed by HEK293, with C-His labeled tag. The total length of Haptoglobin Protein, Rat (HEK293, His) is 347 a.a., with molecular weight of ~38.1 kDa.

ACLP 作为胶原纤维生成的正调节因子，可能在细胞外基质的组织和重塑中发挥着至关重要的作用。它的作用延伸到积极调节脂肪细胞中的 MAP 激酶活性，有助于增加脂肪细胞增殖并减少脂肪细胞分化。此外，ACLP 可能作为巨噬细胞中 NF-κ-B 活性的正调节因子，促进 I-κ-B-α (NFKBIA) 的磷酸化和随后的降解，最终增强巨噬细胞的炎症反应性。此外，ACLP 表现出转录抑制活性，表明其参与基因表达的调节。

Rat

HEK293

C-His

P06866 (M1-N347)

24464  [NCBI]

Approximately 38.1 kDa

Greater than 90% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.