HEPACAM 蛋白, Human (HEK293, His)

HEPACAM proteins are key regulators of cell motility, interacting with the extracellular matrix to inhibit cell growth and maintain cellular homeostasis. HEPACAM forms homodimers through cis interactions, is a component of the MLC1, TRPV4, AQP4 and ATP1B1 complexes and participates in key molecular interactions. HEPACAM Protein, Human (HEK293, His) is the recombinant human-derived HEPACAM protein, expressed by HEK293 , with C-6*His labeled tag. The total length of HEPACAM Protein, Human (HEK293, His) is 207 a.a., with molecular weight of 35-45 kDa.

HEPACAM 蛋白是细胞运动和与细胞外基质相互作用的复杂协调中的关键调节因子。它表现出通过抑制增殖来抑制细胞生长的潜力，表明它在维持细胞稳态方面发挥着作用。该蛋白质形成同型二聚体，二聚化主要通过细胞表面的顺式相互作用发生。值得注意的是，它是包含 MLC1、TRPV4、AQP4 和 ATP1B1 的复合体的组成部分，突显了它参与对各种细胞过程至关重要的分子相互作用网络。HEPACAM 的多方面参与强调了它在细胞动力学和生长调节的复杂景观中的重要性。

Human

HEK293

C-6*His

Q14CZ8/NP_689935.2 (V34-S240)

220296  [NCBI]

VNITSPVRLIHGTVGKSALLSVQYSSTSSDRPVVKWQLKRDKPVTVVQSIGTEVIGTLRPDYRDRIRLFENGSLLLSDLQLADEGTYEVEISITDDTFTGEKTINLTVDVPISRPQVLVASTTVLELSEAFTLNCSHENGTKPSYTWLKDGKPLLNDSRMLLSPDQKVLTITRVLMEDDDLYSCMVENPISQGRSLPVKITVYRRSS

35-45 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.