HOXA1 蛋白, Human (His)

The HOXA1 protein is a sequence-specific transcription factor that complexly regulates multiple developmental processes in the brainstem, inner and outer ears, abducens nerves, and cardiovascular development. It also plays a key role in cognitive and behavioral processes. HOXA1 Protein, Human (His) is the recombinant human-derived HOXA1 protein, expressed by E. coli , with N-His labeled tag.

HOXA1 蛋白作为序列特异性转录因子，复杂地调节包括脑干、内耳和外耳、外展神经和心血管发育在内的多种发育过程。此外，它在认知和行为过程中发挥着关键作用。HOXA1 是沿着前后轴赋予特定位置特征的发育调节系统的一部分，主要影响前部身体结构，并有助于后脑节段的维持或生成。其转录激活取决于 PBX1A 和 PKNOX1 的存在。在细胞核中，HOXA1 通过 TPR 重复结构域与 OGT 相互作用。此外，它与转录因子 PBX1 形成 DNA 结合异二聚体，突出了其在协调复杂发育程序中的多方面作用。

Human

E. coli

N-His

P49639-1 (M1-H335)

3198  [NCBI]

Approximately 42 kDa

Greater than 85% as determined by reducing SDS-PAGE

溶液.

Supplied as a 0.22 μm filtered solution in 50 mM Tris, 30% Glycerol, pH 7.5.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.