IDI2 蛋白, Human (His)

IDI2 protein plays a crucial role in catalyzing the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP), leading to the formation of its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). This enzymatic activity is a key step in the biosynthetic pathway, contributing to the generation of essential building blocks for various cellular processes. IDI2 Protein, Human (His) is the recombinant human-derived IDI2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of IDI2 Protein, Human (His) is 227 a.a., with molecular weight of 28-31 kDa.

异戊烯二磷酸 Delta 异构酶 2 (IDI2) 通过催化异戊烯二磷酸 (IPP) 的 1,3-烯丙基重排，将其转化为其高度亲电子的烯丙基异构体二甲基烯丙基二磷酸 (DMAPP)，在类异戊二烯生物合成中发挥关键作用。这种酶活性是甲羟戊酸途径中的关键步骤，甲羟戊酸途径负责类异戊二烯的产生，类异戊二烯是参与各种细胞过程（包括蛋白质异戊二烯化和甾醇生物合成）的必需化合物。IDI2 催化 IPP 异构化为 DMAPP 的能力对于生成多种类异戊二烯化合物至关重要，这些类异戊二烯化合物可作为细胞代谢中多种生物分子的前体。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

E. coli

N-6*His

Q9BXS1 (M1-V227)

91734  [NCBI]

MSDINLDWVDRRQLQRLEEMLIVVDENDKVIGADTKRNCHLNENIEKGLLHRAFSVVLFNTKNRILIQQRSDTKVTFPGYFTDSCSSHPLYNPAELEEKDAIGVRRAAQRRLQAELGIPGEQISPEDIVFMTIYHHKAKSDRIWGEHEICYLLLVRKNVTLNPDPSETKSILYLSQEELWELLEREARGEVKVTPWLRTIAERFLYRWWPHLDDVTPFVELHKIHRV

28-31 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 1 mM DTT, 0.1 mM PMSF, pH 8.0.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.