2. 重组蛋白
  3. Receptor Proteins
  4. Cell Adhesion Molecules (CAMs)
  5. Immunoglobulin-like Cell Adhesion Molecules
  6. Immunoglobulin Superfamily Member 11 (IGSF11)
  7. IGSF11 蛋白, Human (HEK293, His)

IGSF11 蛋白, Human (HEK293, His)

目录号: HY-P76411
产品使用指南

Immunoglobulin superfamily member 11 最初被确定为免疫球蛋白超家族的成员，并已被揭示以非钙依赖性方式作为 CAM 发挥作用。Immunoglobulin superfamily member 11 是优先在脑内表达的嗜同种黏附分子，是突触后支架蛋白 PSD-95 和 AMPA 谷氨酸受体 (AMPARs) 的双结合伴侣。IGSF11 蛋白, Human (HEK293, His) 是重组的 IGSF11 蛋白，由 HEK293 表达，带有 C-His 标签。IGSF11 蛋白, Human (HEK293, His) 全长 218 个氨基酸，分子量约为 ~36 KDa。

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描述

Immunoglobulin superfamily member 11 was originally identified as a member of the immunoglobulin superfamily, and it has been revealed to function as a CAM in a calciumindependent manner. Immunoglobulin superfamily member 11, a homophilic adhesion molecule that preferentially expressed in the brain, is a dual-binding partner of the postsynaptic scaffolding protein PSD-95 and AMPA glutamate receptors (AMPARs). IGSF11 Protein, Human (HEK293, His) is the recombinant human-derived IGSF11 protein, expressed by HEK293 , with C-His labeled tag. The total length of IGSF11 Protein, Human (HEK293, His) is 218 a.a., with molecular weight of ~36 KDa.
研究背景

Immunoglobulin superfamily member 11 是优先表达于脑和睾丸的免疫球蛋白超家族成员。Immunoglobulin superfamily member 11 与柯萨奇病毒和腺病毒受体以及内皮细胞选择性黏附分子具有显著的同源性。Immunoglobulin superfamily member 11 使离子型谷氨酸受体结合并通过质膜黏附分子参与嗜同种细胞黏附[1][2][3][4]。
种属

Human
表达系统

HEK293
标签

C-His
蛋白编号

AAH34411.1 (E23-G240)
基因 ID
蛋白结构
N-term
IGSF11 (E23-G240)
Accession # AAH34411.1
His
C-term
同用名
BT-IgSF; CT119; CXADRL1; Igsf13; VSIG3
分子量

Approximately 36 kDa.
纯度

Greater than 85% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

IGSF11 Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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