1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Interleukin & Receptors
  4. IL-13
  5. IL-13 蛋白, Rat

IL-13 蛋白, Rat 是由许多细胞类型分泌的细胞因子,尤其是 Th2 细胞。IL-13 蛋白 是过敏性炎症和疾病的重要介质。

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100 μg   询价  

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描述

IL-13 Protein, Rat is a cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, that is an important mediator of allergic inflammation and disease.

研究背景

白细胞介素(IL)-13在过敏性哮喘的发病机制中发挥着关键作用。在动物模型中,被动施用其单克隆抗体或可溶性受体来阻断过量产生的IL-13已被证明可以有效控制气道过敏反应,但这些方法存在半衰期短、成本高和可能产生不良反应的缺点。IL-13诱导Ca2+激活氯通道的基因表达,刺激上皮细胞分化,促进粘蛋白基因表达和释放。IL-13 在哮喘发病机制中发挥着关键作用[1]

种属

Rat

表达系统

E. coli

标签

Tag Free

蛋白编号

P42203 (T19-H131)

基因 ID
蛋白结构
N-term
IL-13 (T19-H131)
Accession # P42203
C-term
中文名
白介素-13 蛋白
同用名
Interleukin-13; IL-13; T-Cell Activation Protein P600; IL13
氨基酸序列

TPGPVRRSTSPPVALRELIEELSNITQDQKTSLCNSSMVWSVDLTAGGFCAALESLTNISSCNAIHRTQRILNGLCNQKASDVASSPPDTKIEVAQFISKLLNYSKQLFRYGH

预测分子量
12.3 kDa
纯度

Greater than 98% as determined by reducing SDS-PAGE. Greater than 98% as determined by SEC-HPLC.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
参考文献
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
IL-13 Protein, Rat
目录号:
HY-P7099
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