1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Interleukin & Receptors
  4. IL-16
  5. IL-16 蛋白, Mouse (His)

IL-16 蛋白, Mouse (His)

目录号: HY-P72590
COA 产品使用指南

IL-16 蛋白是一种细胞因子,在免疫调节和炎症中发挥着重要作用。它调节各种免疫细胞的激活和迁移,例如 T 细胞和单核细胞。了解 IL-16 蛋白的功能有助于研究免疫反应并开发针对炎症和自身免疫性疾病的靶向疗法。IL-16 蛋白, Mouse (His) 是重组的 IL-16 蛋白,由 E. coli 表达,带有 N-6*His 标签。IL-16 蛋白, Mouse (His) 全长 118 个氨基酸,分子量为 14-16 kDa。

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规格 价格 是否有货 数量
10 μg ¥1680 In-stock
50 μg ¥5040 In-stock
100 μg   询价  

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描述

IL-16 Protein, a cytokine, plays a significant role in immune regulation and inflammation. It modulates the activation and migration of various immune cells, such as T cells and monocytes. Understanding the functions of IL-16 Protein can aid in studying immune responses and developing targeted therapies for inflammatory and autoimmune diseases. IL-16 Protein, Mouse (His) is the recombinant mouse-derived IL-16 protein, expressed by E. coli , with N-6*His labeled tag. The total length of IL-16 Protein, Mouse (His) is 118 a.a., with molecular weight of 14-16 kDa.

研究背景

IL-16 是一种多面蛋白质,可引发 CD4+ 淋巴细胞、单核细胞和嗜酸性粒细胞的迁移反应。它在启动 CD4+ T 细胞对白细胞介素 2 (IL-2) 和白细胞介素 15 (IL-15) 的反应中发挥着关键作用,同时诱导白细胞介素 2 受体的表达。此外,IL-16 作为 CD4 的配体,促进复杂的相互作用。值得注意的是,IL-16 的异构体 1 被认为具有支架蛋白的功能,为细胞膜内的离子通道提供结构锚定。

种属

Mouse

表达系统

E. coli

标签

N-6*His

蛋白编号

O54824 (S1205-S1322)

基因 ID

16170  [NCBI]

蛋白结构
N-term
6*His
IL-16 (S1205-S1322)
Accession # O54824
C-term
同用名
Pro-interleukin-16; Interleukin-16; IL-16; Lymphocyte chemoattractant factor; LCF
氨基酸序列

SAASASAASDISVESKEATVCTVTLEKTSAGLGFSLEGGKGSLHGDKPLTINRIFKGTEQGEMVQPGDEILQLAGTAVQGLTRFEAWNVIKALPDGPVTIVIRRTSLQCKQTTASADS

分子量

14-16 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

性状

无菌粉末.

组分

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

IL-16 Protein, Mouse (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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