2. 重组蛋白
  3. Enzymes & Regulators
  4. IMPA1 蛋白, Human (His)

IMPA1 蛋白, Human (His)

目录号: HY-P70335
产品使用指南

IMPA1蛋白为磷脂酰肌醇和多磷酸肌醇的合成提供必需的肌醇。IMPA1 蛋白, Human (His) 是重组的 IMPA1 蛋白，由 E. coli 表达，带有 N-6*His 标签。IMPA1 蛋白, Human (His) 全长 277 个氨基酸，分子量约为 ~30.0 kDa。

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规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

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描述

IMPA1 protein provides essential inositol for the synthesis of phosphatidylinositol and polyphosphate inositol. IMPA1 Protein, Human (His) is the recombinant human-derived IMPA1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of IMPA1 Protein, Human (His) is 277 a.a., with molecular weight of ~30.0 kDa.
研究背景

IMPA1 蛋白在提供合成磷脂酰肌醇和多磷酸肌醇所必需的肌醇方面发挥着至关重要的作用。此外，它还被认为是锂在大脑中作用的药理学靶点。IMPA1 具有广泛的底物特异性，可以利用多种底物，包括肌醇一磷酸、肌醇 1,3-二磷酸、肌醇 1,4-二磷酸、鲨肌醇磷酸、D-半乳糖 1-磷酸、葡萄糖- 1-磷酸、葡萄糖-6-磷酸、果糖-1-磷酸、β-甘油磷酸和2'-AMP。
种属

Human
表达系统

E. coli
标签

N-6*His
蛋白编号

P29218 (M1-D277)
基因 ID
蛋白结构
N-term
6*His
IMPA1 (M1-D277)
Accession # P29218
C-term
同用名
rHuInositol monophosphatase 1/IMPA1, His; Inositol Monophosphatase 1; IMP 1; IMPase 1; Inositol-1(or 4)-Monophosphatase 1; Lithium-Sensitive Myo-Inositol Monophosphatase A1; IMPA1; IMPA
氨基酸序列

MADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDED

分子量

Approximately 30.0 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

IMPA1 Protein, Human (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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