1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Peptide Hormone & Neuropeptides
  4. Insulin
  5. Insulin 蛋白, Bovine

Insulin 蛋白, Bovine

目录号: HY-P701240
产品使用指南

胰岛素蛋白调节体内的葡萄糖代谢。它与胰岛素受体结合,激活促进葡萄糖摄取和储存的信号通路。胰岛素蛋白还调节脂质代谢和蛋白质合成。了解其功能对于开发糖尿病和代谢紊乱的治疗方法至关重要。Insulin 蛋白, Bovine 是重组的蛋白二聚体复合物,包含 牛胰岛素蛋白,由 P. pastoris 酵母表达,不带标签。Insulin 蛋白, Bovine ,分子量约为 ~6 kDa。

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重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
100 mg 询问价格 & 货期

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描述

Insulin Protein regulates glucose metabolism in the body. It binds to insulin receptors, activating signaling pathways that facilitate glucose uptake and storage. Insulin Protein also regulates lipid metabolism and protein synthesis. Understanding its functions is crucial for developing treatments for diabetes and metabolic disorders. Insulin Protein, Bovine is a recombinant protein dimer complex containing bovine-derived Insulin protein, expressed by P. pastoris, with tag free. Insulin Protein, Bovine, has molecular weight of ~6 kDa.

研究背景

胰岛素是葡萄糖稳态的关键激素,在降低血糖浓度方面发挥着至关重要的作用。它的作用超出了血糖控制范围,因为它增强了细胞对单糖、氨基酸和脂肪酸的渗透性。此外,胰岛素促进肝脏中的糖酵解、磷酸戊糖循环和糖原合成等代谢过程,有助于整体能量调节。在结构上,胰岛素由异二聚体排列组成,由通过两个二硫键连接的 B 链和 A 链组成。胰岛素的多方面功能强调了其在协调代谢反应和维持生理平衡方面的重要性。

种属

Bovine

表达系统

P. pastoris

标签

Tag Free

蛋白编号

P01317 (F25-A54&G85-N105)

基因 ID

/

蛋白结构
N-term
Insulin (F25-A54&G85-N105)
Accession # P01317
C-term
同用名
Insulin; INS; IDDM; ILPR; IRDN; MODY10
氨基酸序列

AFVNQHLCGSHLVEALYLVCGERGFFYTPKA&GIVEQCCASVCSLYQLENYCN

分子量

Approximately 6 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

< 0.1 EU/μg of protein by gel clotting method

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Insulin Protein, Bovine
目录号:
HY-P701240
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