2. 重组蛋白
  3. Cytokines and Growth Factors
  4. Interferon & Receptors
  5. IFN-alpha
  6. Interferon alpha-B
  7. IFN-alpha B/IFNA8 蛋白, Human (HEK293)

IFN-alpha B/IFNA8 蛋白, Human (HEK293)

目录号: HY-P73861
COA 产品使用指南

IFN-α B/IFNA8 蛋白由巨噬细胞合成，具有有效的抗病毒活性。它刺激必需酶（蛋白激酶和寡腺苷酸合成酶）的产生，这些酶对于细胞防御病毒感染至关重要。IFN-alpha B/IFNA8 蛋白, Human (HEK293) 是重组的 IFN-α B/IFNA8 蛋白，由 HEK293 表达，不带标签。IFN-alpha B/IFNA8 蛋白, Human (HEK293) 全长 166 个氨基酸，分子量约为 ~26 kDa。

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规格 价格 是否有货 数量
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2 μg ￥650 In-stock
10 μg ￥1750 In-stock
50 μg ￥4800 In-stock
100 μg   询价  

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描述

IFN-alpha B/IFNA8 Protein, synthesized by macrophages, displays potent antiviral activities. It stimulates the production of essential enzymes—a protein kinase and an oligoadenylate synthetase—that are pivotal in cellular defense against viral infections. IFN-alpha B/IFNA8 Protein, Human (HEK293) is the recombinant human-derived IFN-alpha B/IFNA8 protein, expressed by HEK293 , with tag free. The total length of IFN-alpha B/IFNA8 Protein, Human (HEK293) is 166 a.a., with molecular weight of ~26 kDa.
研究背景

IFN-α B/IFNA8 蛋白由巨噬细胞产生，具有有效的抗病毒活性。它刺激两种关键酶的产生：蛋白激酶和寡腺苷酸合成酶。这些酶在细胞防御病毒感染方面发挥着至关重要的作用。
生物活性

Measured in antiviral assays using WISH cells infected with vesicular stomatitisvirus (VSV). The ED50 for this effect is 0.2-2 pg/mL.
种属

Human
表达系统

HEK293
标签

Tag Free
蛋白编号

P32881 (C24-E189)
基因 ID
蛋白结构
N-term
IFNA8 (C24-E189)
Accession # P32881
C-term
同用名
IFNA8; IFN-alpha 8; IFN-alpha B2; Interferon alpha-8; Interferon alpha-B
氨基酸序列

CDLPQTHSLGNRRALILLAQMRRISPFSCLKDRHDFEFPQEEFDDKQFQKAQAISVLHEMIQQTFNLFSTKDSSAALDETLLDEFYIELDQQLNDLESCVMQEVGVIESPLMYEDSILAVRKYFQRITLYLTEKKYSSCAWEVVRAEIMRSFSLSINLQKRLKSKE

分子量

Approximately 26 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
性状

溶液.
组分

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
内毒素含量

<1 EU/μg, determined by LAL method.
复溶方法

N/A.

保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
运输条件

Shipping with dry ice.
文件资料

COA (244 KB)

产品使用指南 (1213 KB)

IFN-alpha B/IFNA8 Protein, Human (HEK293) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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