LDLRAD3 蛋白, Human (HEK293, Fc)

LDLRAD3 protein significantly affects the processing of amyloid precursor protein (APP), possibly reducing soluble APP-α (sAPP-α) and increasing the production of amyloid P3 peptide. Suggested regulation of ITCH and NEDD4 E3 ligases. LDLRAD3 Protein, Human (HEK293, Fc) is the recombinant human-derived LDLRAD3 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of LDLRAD3 Protein, Human (HEK293, Fc) is 156 a.a., with molecular weight of ~43.8 KDa.

LDLRAD3 蛋白似乎对淀粉样前体蛋白 (APP) 的加工有显着影响，可能导致可溶性 APP-α (sAPP-α) 的产生减少，并增加淀粉样蛋白 P3 肽的产生。此外，研究表明，它在 ITCH 和 NEDD4 E3 连接酶的活性和降解中发挥调节作用。在微生物感染的情况下，LDLRAD3 充当委内瑞拉马脑炎病毒的受体。这些发现强调了 LDLRAD3 的多功能性质，表明它参与与蛋白质加工、免疫反应和病毒相互作用相关的关键细胞过程。

Human

HEK293

C-hFc

Q86YD5/NP_777562.1 (Q18-T173)

143458  [NCBI]

Approximately 43.8 kDa.

Greater than 90% as determined by reducing SDS-PAGE

溶液

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.