2. 重组蛋白
  3. Cytokines and Growth Factors
  4. Neurotrophic Factors
  5. Leukemia Inhibitory Factor
  6. LIF 蛋白, Mouse (HEK293, His)

LIF 蛋白, Mouse (HEK293, His)

目录号: HY-P73280
产品使用指南

LIF（白血病抑制因子）促进白血病细胞的终末分化，诱导造血细胞和神经元细胞分化。它还刺激肝细胞中的急性期蛋白质合成。LIF 的多方面作用强调了其在调节造血、神经发生和肝脏反应中的重要性。LIF 蛋白, Mouse (HEK293, His) 是重组的 LIF 蛋白，由 HEK293 表达，带有 C-His 标签。LIF 蛋白, Mouse (HEK293, His) 全长 203 个氨基酸，分子量为 35-45 kDa。

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1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

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描述

LIF (Leukemia Inhibitory Factor) prompts terminal differentiation in leukemic cells, inducing hematopoietic and neuronal cell differentiation. It also stimulates acute-phase protein synthesis in hepatocytes. LIF's multifaceted role underscores its significance in regulating hematopoiesis, neurogenesis, and hepatic responses. LIF Protein, Mouse (HEK293, His) is the recombinant mouse-derived LIF protein, expressed by HEK293 , with C-His labeled tag. The total length of LIF Protein, Mouse (HEK293, His) is 203 a.a., with molecular weight of 35-45 kDa.
研究背景

LIF（白血病抑制因子）具有促进白血病细胞终末分化的能力，具有多种活性。值得注意的是，它诱导正常细胞和髓性白血病细胞的造血分化，促进神经元细胞分化，并刺激肝细胞中急性期蛋白的合成。这种多方面的作用强调了 LIF 在协调各种细胞过程中的重要性，有助于调节造血、神经发生和肝脏反应。
种属

Mouse
表达系统

HEK293
标签

C-His
蛋白编号

P09056 (M1-F203)
基因 ID

16878  [NCBI]
蛋白结构
N-term
LIF (M1-F203)
Accession # P09056
His
C-term
同用名
LIF; Leukemia inhibitory factor; HILDA; D factor; MLPLI
分子量

35-45 kDa
纯度

Greater than 85% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

LIF Protein, Mouse (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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