LSP1 蛋白, Human (HEK293, His)

The LSP1 protein may play an important role in mediating neutrophil activation and chemotaxis, suggesting its involvement in immune responses. LSP1 is known to bind actin and may influence cytoskeletal dynamics critical for cell migration. LSP1 Protein, Human (HEK293, His) is the recombinant human-derived LSP1 protein, expressed by HEK293 , with C-His labeled tag. The total length of LSP1 Protein, Human (HEK293, His) is 339 a.a., with molecular weight of ~38.7 kDa.

LSP1 蛋白可能在介导中性粒细胞活化和趋化性方面发挥重要作用，强调其参与与免疫反应相关的复杂过程。从功能上讲，LSP1 已知可结合肌动蛋白，这表明它参与细胞骨架动力学，而细胞骨架动力学是细胞迁移和趋化反应不可或缺的一部分。LSP1 调节中性粒细胞活化、趋化性及其与肌动蛋白相互作用的精确机制仍然是人们感兴趣的领域，需要进一步研究以揭示其在免疫细胞反应的复杂协调中的特定功能和分子贡献。

Human

HEK293

C-6*His

P33241-1 (M1-P339)

4046  [NCBI]

MAEASSDPGAEEREELLGPTAQWSVEDEEEAVHEQCQHERDRQLQAQDEEGGGHVPERPKQEMLLSLKPSEAPELDEDEGFGDWSQRPEQRQQHEGAQGALDSGEPPQCRSPEGEQEDRPGLHAYEKEDSDEVHLEELSLSKEGPGPEDTVQDNLGAAGAEEEQEEHQKCQQPRTPSPLVLEGTIEQSSPPLSPTTKLIDRTESLNRSIEKSNSVKKSQPDLPISKIDQWLEQYTQAIETAGRTPKLARQASIELPSMAVASTKSRWETGEVQAQSAAKTPSCKDIVAGDMSKKSLWEQKGGSKTSSTIKSTPSGKRYKFVATGHGKYEKVLVEGGPAP

Approximately 60 kDa due to the glycosylation

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.