1. 重组蛋白
  2. CD Antigens
  3. Macrophage CD Proteins Monocyte CD Proteins Stem Cell CD Proteins Dendritic Cell CD Proteins Epithelial cell CD Proteins
  4. CD68
  5. CD68 蛋白, Human (HEK293, Fc)

CD68 蛋白, Human (HEK293, Fc)

目录号: HY-P70028
COA 产品使用指南

CD68 蛋白对于组织巨噬细胞的吞噬活动至关重要,包括溶酶体代谢以及与细胞和病原体的相互作用。它与凝集素或选择素结合,帮助特定巨噬细胞亚群的靶向迁移。CD68从内体和溶酶体到质膜的快速再循环使得巨噬细胞能够爬行或与带有选择素的底物和其他细胞相互作用。CD68 蛋白, Human (HEK293, Fc) 是重组的 CD68 蛋白,由 HEK293 表达,带有 C-hFc 标签。CD68 蛋白, Human (HEK293, Fc) 全长 299 个氨基酸,分子量为 70-100 kDa。

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重组蛋白定制服务

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
10 μg ¥890 In-stock
50 μg ¥2500 In-stock
100 μg   询价  

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描述

CD68 protein is essential for phagocytic activities in tissue macrophages, including lysosomal metabolism and interactions with cells and pathogens. It binds to lectins or selectins, aiding targeted migration of specific macrophage subsets. CD68's rapid recirculation from endosomes and lysosomes to the plasma membrane allows macrophages to crawl or interact with selectin-bearing substrates and other cells. CD68 Protein, Human (HEK293, Fc) is the recombinant human-derived CD68 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD68 Protein, Human (HEK293, Fc) is 299 a.a., with molecular weight of 70-100 kDa.

研究背景

CD68 蛋白被认为在组织巨噬细胞进行的各种吞噬活动中发挥着至关重要的作用,包括细胞内溶酶体代谢以及细胞外与细胞和病原体的相互作用。它能够结合组织和器官特异性凝集素或选择素,促进特定巨噬细胞亚群靶向迁移到特定位点。CD68 从内体和溶酶体快速再循环到质膜,使巨噬细胞能够爬过带有选择素的底物或与其他细胞相互作用。

种属

Human

表达系统

HEK293

标签

C-hFc

蛋白编号

P34810 (N22-I320)

基因 ID

968  [NCBI]

蛋白结构
N-term
CD68 (N22-I320)
Accession # P34810
hFc
C-term
同用名
rHuMacrosialin/CD68, Fc ; CD68 antigenmacrophage antigen CD68; CD68 molecule; CD68; gp110; Macrosialin; SCARD1; SRD1; SR-D1
氨基酸序列

NDCPHKKSATLLPSFTVTPTVTESTGTTSHRTTKSHKTTTHRTTTTGTTSHGPTTATHNPTTTSHGNVTVHPTSNSTATSQGPSTATHSPATTSHGNATVHPTSNSTATSPGFTSSAHPEPPPPSPSPSPTSKETIGDYTWTNGSQPCVHLQAQIQIRVMYTTQGGGEAWGISVLNPNKTKVQGSCEGAHPHLLLSFPYGHLSFGFMQDLQQKVVYLSYMAVEYNVSFPHAAQWTFSAQNASLRDLQAPLGQSFSCSNSSIILSPAVHLDLLSLRLQAAQLPHTGVFGQSFSCPSDRSI

分子量

70-100 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

性状

无菌粉末.

组分

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD68 Protein, Human (HEK293, Fc)
目录号:
HY-P70028
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