MAOB 蛋白, Human (Active, sf9, His)

MAOB Protein, Human (Active, sf9, His) is the recombinant human-derived MAOB protein, expressed by Sf9 insect cells, with N-His tag. This product contains detergent and is not suitable for cell-related experiments.

MAOB 是一种催化氧化脱氨反应的酶，主要作用于一级胺和部分二级胺（如神经递质），同时也参与外源性胺类（包括三级胺神经毒素 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)）的代谢。其反应伴随氧还原为过氧化氢，并在中枢神经系统及外周组织中参与神经活性和血管活性胺类的代谢。该酶优先降解 benzylamine 和 phenylethylamine。by similar: 相关研究进一步支持了其在胺类代谢中的关键作用。

Measured by its ability to produce hydrogen peroxide during the oxidation of benzylamine. The specific activity is >35 pmol/min/μg.

Human

Sf9 insect cells

N-His

P27338-1 (S2-V520)

4129

Full Length of Isoform-1 Mature Protein

SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV

Approximately 55 kDa, based on SDS-PAGE under reducing conditions.

Greater than 90% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH 7.5 with glycerol as protectant. Due to the cytotoxicity of the detergent, this product is not appropriate for cell-based experiments.

<1 EU/μg, determined by LAL method.

Please use rapid thawing with running water to thaw the protein.

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.