METAP1/Methionine aminopeptidase 1 蛋白, Human

METAP1 (or methionine aminopeptidase 1) plays a crucial role in protein synthesis by co-translationally removing N-terminal methionine from nascent proteins. This enzymatic activity is particularly relevant when the second residue in the primary sequence is small and uncharged (including residues such as Ala, Cys, Gly, Pro, Ser, Thr or Val). METAP1/Methionine aminopeptidase 1 Protein, Human is the recombinant human-derived METAP1/Methionine aminopeptidase 1 protein, expressed by E. coli , with tag free. The total length of METAP1/Methionine aminopeptidase 1 Protein, Human is 386 a.a., with molecular weight of 38-50 kDa.

METAP1（或蛋氨酸氨肽酶 1）是一种对蛋白质合成调节至关重要的蛋白质。它通过共翻译消除新生蛋白质中的 N 端甲硫氨酸，特别是当一级序列中的第二个残基是小的且不带电荷的氨基酸（例如 Met-Ala、Cys、Gly、Pro、Ser、Thr 或 Val）时。这种活性对于蛋白质的正常成熟和功能至关重要。此外，METAP1 在细胞过程中发挥着关键作用，是细胞周期正常进展所必需的。它参与细胞周期强调了它在基本生物事件中的重要性，进一步强调了它在维持细胞稳态和正常功能中的作用。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

E. coli

Tag Free

P53582 (M1-F386)

23173  [NCBI]

MAAVETRVCETDGCSSEAKLQCPTCIKLGIQGSYFCSQECFKGSWATHKLLHKKAKDEKAKREVSSWTVEGDINTDPWAGYRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEILTRRLDSARPHFMSQF

38-50 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Glycine, 10% Sucrose, 10% Glycerol, 0.02% Tween80, pH 3.5.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.