MIP-3 alpha/CCL20 蛋白, Rhesus macaque (GST)

MIP-3 alpha/CCL20 Protein, part of the intercrine beta (chemokine CC) family, is instrumental in regulating immune cell migration and inflammation. Recognized for attracting and activating dendritic cells and memory T cells, it plays a vital role in immune response at infection or inflammation sites. Operating via its receptor CCR6, MIP-3 alpha/CCL20 initiates events that enhance immune cell recruitment and activation. As a potential therapeutic target, it holds promise for immune response modulation and inflammation control in diverse pathological conditions. MIP-3 alpha/CCL20 Protein, Rhesus macaque (GST) is the recombinant Rhesus Macaque-derived MIP-3 alpha/CCL20 protein, expressed by E. coli, with N-GST labeled tag. The total length of MIP-3 alpha/CCL20 Protein, Rhesus macaque (GST) is 70 a.a., with molecular weight of 35.1 kDa.

MIP-3 α/CCL20 蛋白属于间分泌 β（趋化因子 CC）家族，这是一组参与免疫细胞迁移和炎症调节的趋化因子。这种蛋白质因其在吸引和激活免疫细胞（特别是树突状细胞和记忆 T 细胞）到感染或炎症部位方面的作用而闻名。MIP-3 alpha/CCL20 通过与其受体 CCR6 结合发挥作用，并启动一系列促进免疫细胞募集和激活的细胞事件。它在针对病原体的免疫反应中发挥着至关重要的作用，并且还参与某些炎症性疾病的发展。MIP-3 α/CCL20 被认为是调节免疫反应和控制各种病理条件下炎症的潜在治疗靶点。

Rhesus Macaque

E. coli

N-GST

Q8HYP6 (A27-M96)

574182  [NCBI]

ASNFDCCLRYTDRILHPKFIVGFTQQLANETCDINAVVFHTKKGLSVCANPKQTWVKLIVRRLSKKINKM

35.1 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.