MSP/MST1 蛋白, Mouse (C677A, HEK293)

The MSP/MST1 protein, encoded by this gene, is predicted to have receptor tyrosine kinase binding activity. It is involved in various processes, including embryo implantation, mammary duct growth, and regulation of mammary gland cell proliferation. The protein is mainly found in the vacuole and expressed in tissues like the esophagus, liver, pharynx, and stomach. Notably, the gene shows liver-biased expression in both adult and embryonic stages. MSP/MST1 Protein, Mouse (C677A, HEK293) is the recombinant mouse-derived MSP/MST1 protein, expressed by HEK293 , with tag free. and C677A mutation. The total length of MSP/MST1 Protein, Mouse (C677A, HEK293) is 698 a.a., with molecular weight of 92 & 60.5 & 32-36 kDa, respectively.

该基因编码 MSP/MST1 蛋白，预计具有受体酪氨酸激酶结合活性。它在胚胎着床、乳腺导管终芽生长、乳腺上皮细胞增殖的正向调节等多种过程中发挥上游作用。该蛋白主要位于液泡中，在食管上皮、肝脏、肝实质、咽上皮和胃室前区上皮等组织中表达。值得注意的是，在参考数据集中，该基因在成人和胚胎阶段的肝脏中均表现出偏向表达。

Measured by its ability to inhibit the proliferation of Hela cell. The ED₅₀ for this effect is 4.080 ng/ml, corresponding to a specific activity is 2.45×10^5 units/mg.

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  Measured by its ability to inhibit the proliferation of Hela cell. The ED₅₀ for this effect  is 4.080 ng/mL, corresponding to a specific activity is 2.45×10⁵ units/mg.

Mouse

HEK293

Tag Free

NP_032269 (Q19-E716, C677A)

15235  [NCBI]

QRSPLNDFQLFRGTELRNLLHTAVPGPWQEDVADAEECARRCGPLLDCRAFHYNMSSHGCQLLPWTQHSLHTQLYHSSLCHLFQKKDYVRTCIMDNGVSYRGTVARTAGGLPCQAWSRRFPNDHKYTPTPKNGLEENFCRNPDGDPRGPWCYTTNRSVRFQSCGIKTCREAVCVLCNGEDYRGEVDVTESGRECQRWDLQHPHSHPFQPEKFLDKDLKDNYCRNPDGSERPWCYTTDPNVEREFCDLPSCGPNLPPTVKGSKSQRRNKGKALNCFRGKGEDYRGTTNTTSAGVPCQRWDAQSPHQHRFVPEKYACKDLRENFCRNPDGSEAPWCFTSRPGLRMAFCHQIPRCTEELVPEGCYHGSGEQYRGSVSKTRKGVQCQHWSSETPHKPQFTPTSAPQAGLEANFCRNPDGDSHGPWCYTLDPDILFDYCALQRCDDDQPPSILDPPDQVVFEKCGKRVDKSNKLRVVGGHPGNSPWTVSLRNRQGQHFCGGSLVKEQWVLTARQCIWSCHEPLTGYEVWLGTINQNPQPGEANLQRVPVAKAVCGPAGSQLVLLKLERPVILNHHVALICLPPEQYVVPPGTKCEIAGWGESIGTSNNTVLHVASMNVISNQECNTKYRGHIQESEICTQGLVVPVGACEGDYGGPLACYTHDAWVLQGLIIPNRVCARPRWPAIFTRVSVFVDWINKVMQLE

92 & 60.5 & 32-36 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.