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  3. MZB1/PERP1 蛋白, Human (HEK293, Fc)

MZB1/PERP1 蛋白, Human (HEK293, Fc)

目录号: HY-P77094
产品使用指南

MZB1/PERP1 蛋白与 IgM 重链和轻链结合,帮助 IgM 组装和分泌。它充当分子伴侣或氧化还原酶,并表现出低氧化还原酶活性。MZB1/PERP1 蛋白, Human (HEK293, Fc) 是重组的 MZB1/PERP1 蛋白,由 HEK293 表达,带有 C-hFc 标签。

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描述

MZB1/PERP1 protein binds to IgM heavy and light chains and helps IgM assembly and secretion. It acts as a molecular chaperone or oxidoreductase and exhibits low oxidoreductase activity. MZB1/PERP1 Protein, Human (HEK293, Fc) is the recombinant human-derived MZB1/PERP1 protein, expressed by HEK293 , with C-hFc labeled tag.

研究背景

MZB1/PERP1 蛋白与免疫球蛋白 M (IgM) 重链和轻链结合,促进 IgM 的组装和分泌。鉴于其氧化还原酶活性水平较低(通过相似性),其影响可能源于其作为分子伴侣或氧化还原酶的作用。同工型 2 可能参与细胞凋亡的调节。此外,MZB1/PERP1 通过监督 Ca(2+) 储存、抗体分泌和整合素激活,有助于外周 B 细胞功能的多样化。作为一种激素调节的脂肪因子和促炎细胞因子,它与慢性炎症有关,影响细胞扩张并减弱脂肪细胞中的胰岛素反应。此外,MZB1/PERP1 可能在胰岛素抵抗的发生中发挥作用。

种属

Human

表达系统

HEK293

标签

C-hFc

蛋白编号

Q8WU39-1 (D23-T185)

基因 ID
蛋白结构
N-term
MZB1 (D23-T185)
Accession # Q8WU39-1
hFc
C-term
同用名
Marginal zone B- and B1-cell-specific protein; MEDA7; PACAP
分子量

Approximately 44.9 kDa.

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

MZB1/PERP1 Protein, Human (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
MZB1/PERP1 Protein, Human (HEK293, Fc)
目录号:
HY-P77094
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