2. 重组蛋白
  3. CAR-T related Proteins Receptor Proteins
  4. Cell Adhesion Molecules (CAMs)
  5. Immunoglobulin-like Cell Adhesion Molecules
  6. Nectin-4
  7. Nectin-4 蛋白, Cynomolgus (HEK293, His)

Nectin-4 蛋白, Cynomolgus (HEK293, His)

目录号: HY-P70188
产品使用指南

Nectin-4蛋白是Nectin家族的重要成员，在细胞粘附和信号传导中发挥着至关重要的作用，从而影响生理功能。它在介导细胞间相互作用中的作用强调了它在组织组织中的重要性。Nectin-4 蛋白, Cynomolgus (HEK293, His) 是重组的 Nectin-4 蛋白，由 HEK293 表达，带有 C-6*His 标签。Nectin-4 蛋白, Cynomolgus (HEK293, His) 全长 318 个氨基酸，分子量为 38-50 kDa。

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100 μg   询价  

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描述

Nectin-4 protein is an important member of the Nectin family and plays a vital role in cell adhesion and signaling, thereby affecting physiological functions. Its role in mediating cell-cell interactions emphasizes its importance in tissue organization. Nectin-4 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Nectin-4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Nectin-4 Protein, Cynomolgus (HEK293, His) is 318 a.a., with molecular weight of 38-50 kDa.
研究背景

Nectin-4 蛋白是 Nectin 家族的重要成员，对细胞粘附和信号传导过程有显着贡献。作为该家族的一部分，Nectin-4 在介导细胞间相互作用、影响各种生理和发育功能方面发挥着关键作用。它参与细胞粘附表明对组织组织和维护的影响。此外，Nectin-4 因其在癌症中的作用而受到关注，特别是在促进肿瘤细胞侵袭和转移方面。Nectin-4 蛋白属于 nectin 家族，强调了其在基本细胞过程中的重要性及其作为各种病理条件下治疗靶点的潜在意义。
种属

Cynomolgus
表达系统

HEK293
标签

C-6*His
蛋白编号

L0N6D9 (G32-S349)
基因 ID

102127936  [NCBI]
蛋白结构
N-term
Nectin-4 (G32-S349)
Accession # L0N6D9
6*His
C-term
同用名
rCynPoliovirus receptor-related protein 4-like/Nectin-4, His; PVRL4; Nectin-4; Ig superfamily receptor LNIR; Poliovirus receptor-related protein 4; PRR4; LNIR
氨基酸序列

GELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARADAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHVGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSAS

分子量

38-50 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

Nectin-4 Protein, Cynomolgus (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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