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  4. NELL2 蛋白, Human (sf9, His)

NELL2 蛋白, Human (sf9, His)

目录号: HY-P75936
COA 产品使用指南

NELL2 蛋白对神经元存活至关重要，可调节 MAPK 通路并调节下丘脑促性腺激素释放激素 (GNRH) 的分泌，从而影响青春期控制。NELL2 形成同源三聚体并与 PKC beta-1 结合，表明其调节功能中存在复杂的分子相互作用。NELL2 蛋白, Human (sf9, His) 是重组的 NELL2 蛋白，由 Sf9 insect cells 表达，带有 C-His 标签。

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规格 价格 是否有货 数量
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5 μg ￥800 In-stock
10 μg ￥1350 In-stock
50 μg ￥3800 In-stock
100 μg   询价  

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描述

NELL2 protein, crucial for neuron survival, modulates MAPK pathways and regulates hypothalamic gonadotropin-releasing hormone (GNRH) secretion, impacting puberty control. NELL2 forms homotrimers and engages with PKC beta-1, indicating intricate molecular interactions in its regulatory functions. NELL2 Protein, Human (sf9, His) is the recombinant human-derived NELL2 protein, expressed by Sf9 insect cells , with C-His labeled tag.
研究背景

NELL2 蛋白通过调节 MAPK 通路发挥作用，对于神经元的生存是不可或缺的。它在调节下丘脑促性腺激素释放激素 (GNRH) 分泌中起着至关重要的作用，并与青春期的控制有关。在结构上，NELL2 形成同源三聚体，其功能关联延伸至 PKC beta-1 的结合，表明其调节作用涉及复杂的分子相互作用。
种属

Human
表达系统

Sf9 insect cells
标签

C-His
蛋白编号

Q99435 (L22-L816)
基因 ID
蛋白结构
N-term
NELL2 (L22-L816)
Accession # Q99435
His
C-term
同用名
Protein kinase C-binding protein NELL2; NEL-like protein 2; NELL2; NRP2
分子量

Approximately 110 kDa
纯度

Greater than 87% as determined by reducing SDS-PAGE
性状

溶液
组分

Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.0.
内毒素含量

<1 EU/μg, determined by LAL method.
复溶方法

N/A.
保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
运输条件

Shipping with dry ice.
文件资料

COA (209 KB)

产品使用指南 (1213 KB)

NELL2 Protein, Human (sf9, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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