1. 重组蛋白
  2. Receptor Proteins
  3. Neuropilin-2 蛋白, Human (HEK293, Fc)

Neuropilin-2 蛋白, Human (HEK293, Fc)

目录号: HY-P73313
产品使用指南

Neuropilin-2 蛋白是一个关键角色,是信号蛋白 3C 和 3F、VEGF-165、VEGF-145 和 PLGF-2 的高亲和力受体。除了在生长因子中的作用外,Neuropilin-2 在微生物感染中也发挥着关键作用,作为一种受体,促进人类巨细胞病毒以五聚体依赖性方式进入上皮细胞和内皮细胞。Neuropilin-2 蛋白, Human (HEK293, Fc) 是重组的 Neuropilin-2 蛋白,由 HEK293 表达,带有 C-hFc 标签。Neuropilin-2 蛋白, Human (HEK293, Fc) 全长 833 个氨基酸,分子量为 119-129 kDa。

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描述

Neuropilin-2 Protein, a pivotal player, serves as a high-affinity receptor for semaphorins 3C and 3F, VEGF-165, VEGF-145, and PLGF-2. Beyond its role in growth factors, Neuropilin-2 plays a critical function in microbial infection, acting as a receptor facilitating pentamer-dependent entry of human cytomegalovirus into epithelial and endothelial cells. Neuropilin-2 Protein, Human (HEK293, Fc) is the recombinant human-derived Neuropilin-2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Neuropilin-2 Protein, Human (HEK293, Fc) is 833 a.a., with molecular weight of 119-129 kDa.

研究背景

Neuropilin-2 蛋白成为关键参与者,证明了信号蛋白 3C 和 3F、血管内皮生长因子 (VEGF) 的 VEGF-165 和 VEGF-145 亚型以及 PLGF-2 亚型的高亲和力受体作用胎盘生长因子(PGF)。值得注意的是,在微生物感染的情况下,Neuropilin-2 通过充当受体,促进人巨细胞病毒依赖五聚体进入上皮细胞和内皮细胞,从而发挥额外的关键功能。

种属

Human

表达系统

HEK293

标签

C-hFc

蛋白编号

O60462 (Q23-Y855)

基因 ID
蛋白结构
N-term
Neuropilin-2 (Q23-Y855)
Accession # O60462
hFc
C-term
同用名
Neuropilin-2; NRP2; VEGF165R2
分子量

119-129 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

Neuropilin-2 Protein, Human (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Neuropilin-2 Protein, Human (HEK293, Fc)
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HY-P73313
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