OX40/TNFRSF4 蛋白, Human (HEK293, mFc)

OX40/TNFRSF4, a receptor for TNFSF4/OX40L/GP34, crucially acts as a costimulatory molecule in long-term T-cell immunity. Additionally, OX40 functions as a receptor for human herpesvirus 6B/HHV-6B during microbial infections, highlighting its dual role in the adaptive immune response and potential involvement in specific viral interactions. OX40/TNFRSF4 Protein, Human (HEK293, mFc) is the recombinant human-derived OX40/TNFRSF4 protein, expressed by HEK293, with C-mFc labeled tag.

OX40，也称为 TNFRSF4，作为 TNFSF4/OX40L/GP34 的受体发挥作用，并作为与长期 T 细胞免疫相关的关键共刺激分子。除了在免疫调节中的作用外，OX40 还在微生物感染期间充当人类疱疹病毒 6B/HHV-6B 的受体。这种双重功能强调了 OX40 在适应性免疫反应中的重要性及其在特定病毒相互作用中的潜在参与。

Human

HEK293

C-mFc

P43489 (L29-A216)

7293

Partial

Approximately 58-66 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from 0.22 μm filtered solution of PBS, pH7.4 with trehalose as protectant.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.